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Table 2 Comparison of products: (1) User observations

From: Preventing neonatal sepsis in rural Uganda: a cross-over study comparing the tolerance and acceptability of three alcohol-based hand rub formulations

Characteristic

Product; mean (s.d.) [range]

Differences (95% CIs)

  

A (Plain)

B (Perfumed)

C (Bitterant)

A vs. B

A vs. C

B vs. C

  

Time since enrolment (days)

7 (0) [7: 7]

14 (0) [14: 14]

21 (0) [21: 21]

0

0

0

  

Total amount of product used (ml)

64 (27) [5: 100]

83 (17) [25: 100]

91 (11) [50:100]

19 (10: 28)*

27 (18: 35)*

8 (2: 14)*

  

For how many days did you use product?

5.1 (0.5) [3: 7]

5.0 (0.3) [4: 6]

5.1 (0.4) [4: 7]

− 0.1 (− 0.2: 0.1)

0 (− 0.2: 0.2)

− 0.1 (− 0.1: 0.2)

  

Study has changed hand practice.

42 (100)**

43 (100)

43 (100)

0

0

0

  

Number of times hand rub was used at last 10 times:

 

 when breastfeeding your baby

7.1 (2.4) [3: 10]

7.6 (2.2) [3: 10]

7.8 (1.9) [4: 10]

0.5 (− 0.3: 1.3)

0.7 (0.0: 1.4)*

0.2 (− 0.5: 0.9)

  

 when changing your baby’s diaper

6.7 (2.7) [1: 10]

7.0 (2.4) [1: 10]

6.7 (2.5) [2: 10]

0.3 (− 0.7: 1.3)

−0.1 (− 0.9: 0.8)

−0.4 (− 1.2: 0.4)

  

 before friend/family handled your baby

4.7 (2.9) [0: 10]

5.1 (2.7) [0: 10]

5.8 (2.8) [0: 10]

0.4 (− 0.5: 1.3)

1.1 (0.1: 2.1)*

0.7 (− 0.4: 1.7)

  

 before you handled your baby

6.1 (2.9) [1: 10]

7.5 (2.5) [2: 10]

7.3 (2.3) [2: 10]

1.5 (0.3: 2.6)*

1.2 (0.2: 2.2)*

− 0.3 (− 1.1: 0.5)

  

 After you went for a “short call” or to urinate

5.3 (2.8) [1: 10]

5.5 (2.6) [2: 10]

6.1 (2.7) [2: 10]

0.3 (− 0.5: 1.1)

0.9 (− 0.1: 1.8)

0.6 (− 0.4: 1.6)

  

 After you went for a “long call” or to defeacate

4.5 (2.6) [1: 10]

5.6 (2.9) [1: 10]

5.3 (2.7) [1: 10]

1.1 (0.2: 2.0)*

0.8 (− 0.1: 1.7)

− 0.3 (− 1.4: 0.8)

  

Opinion of test product for hand hygiene:

 

 colour (1 = unpleasant, 7 = pleasant)

6.4 (1.0) [2: 7]

6.4 (0.9) [2: 7]

6.5 (0.8) [4: 7]

0.1 (− 0.2: 0.3)

0.1 (− 0.2: 0.4)

0.0 (− 0.3: 0.3)

  

 smell (1 = unpleasant, 7 = pleasant)

5.6 (1.6) [1: 7]

5.9 (1.3) [2: 7]

5.1 (2.0) [1: 7]

0.3 (− 0.3: 0.9)

− 0.6 (− 1.3: 0.2)

− 0.9 (− 1.5: − 0.2)*

  

 texture (1 = very sticky; 7 = not sticky at all)

6.1 (1.2) [1: 7]

6.3 (1.0) [2: 7]

6.0 (1.4) [1: 7]

0.2 (− 0.2: 0.6)

−0.1 (− 0.6: 0.5)

−0.3 (− 0.8: 0.3)

  

 irritation (1 = very irritating; 7 = not irritating)

6.0 (1.3) [2: 7]

6.1 (1.3) [3: 7]

6.2 (1.3) [1: 7]

0.1 (− 0.5: 0.6)

0.2 (− 0.3: 0.8)

0.2 (− 0.4: 0.7)

  

 drying effect (1 = very much; 7 = not at all)

2.8 (2.0) [1: 7]

3.3 (2.3) [1: 7]

2.9 (2.4) [1: 7]

0.5 (− 0.4: 1.4)

0.1 (− 0.7: 1.0)

−0.3 (− 1.3: 0.6)

  

 ease of use (1 = very difficult; 7 = very easy)

6.5 (1.0) [3: 7]

6.7 (0.6) [5: 7]

6.6 (1.0) [1: 7]

0.2 (− 0.1: 0.5)

0.1 (− 0.3: 0.5)

−0.1 (− 0.4: 0.2)

  

 speed of drying (1 = very slow; 7 = very fast)

6.5 (0.6) [5: 7]

6.5 (0.8) [3: 7]

6.7 (0.7) [3: 7]

0.0 (− 0.2: 0.2)

0.2 (0.0: 0.5)

0.2 (− 0.1: 0.5)

  

 application (1 = very unpleasant; 7 = very pleasant)

6.4 (0.9) [4: 7]

6.6 (0.6) [5: 7]

6.7 (0.5) [5: 7]

0.3 (0.0: 0.6)

0.3 (0.0: 0.6)*

0.1 (− 0.2: 0.3)

  

 overall evaluation (1-dissatisfied; 7 = very satisfied)

6.4 (0.9) [3: 7]

6.7 (0.7) [4: 7]

6.2 (1.1) [2: 7]

0.3 (0.0: 0.5)*

− 0.2 (− 0.5: 0.1)

−0.5 (− 0.8: − 0.2)*

  

Do you think hand rub makes it easier to keep your hands clean? (1 = yes, absolutely; 7 = not at all)

1.5 (1.1) [1: 6]

1.3 (0.5) [1: 2]

1.2 (0.5) [1: 3]

− 0.2 (− 0.5: 0.1)

−0.3 (− 0.6: 0.0)*

 0.1 (− 0.3: 0.0)

  

Self-assessment of skin on hands

 

 appearance (1 = abnormal; 7 = normal)

7.0 (0.2) [6: 7]

7.0 (0.2) [6: 7]

7.0 (0.0) [7: 7]

0.0 (− 0.1: 0.1)

0.0 (0.0: 0.1)

0.0 (0.0: 0.1)

  

 intactness (1 = abnormal; 7 = normal)

7.0 (0.2) [6: 7]

7.0 (0.0) [7: 7]

7.0 (0.0) [7: 7]

0.0 (0.0: 0.1)

0.0 (0.0: 0.1)

  

 moisture content (1 = abnormal; 7 = normal)

6.9 (0.4) [5: 7]

7.0 (0.0) [7: 7]

7.0 (0.0) [7: 7]

0.1 (0.0: 0.2)

0.1 (0.0: 0.2)

  

 sensation (1 = abnormal; 7 = normal)

7.0 (0.0) [7: 7]

6.9 (0.3) [5: 7]

7.0 (0.0) [7: 7]

0.0 (− 0.1: 0.0)

0.0 (0.0: 0.1)

  

Frequency of ABHR Use and ABHR Bottle preference

 

 In first 3 months after childbirth, how often on average do you leave your home compound?

never

n (%)

1 (2.3)

3 (7.0)

0

   

1–5 times

n (%)

23 (53.5)

20 (46.5)

17 (39.5)

   

6–10 times

n (%)

11 (25.6)

9 (20.9)

15 (34.9)

p = 0.562

p = 0.051 +

p = 0.320

most weeks

n (%)

5 (11.6)

7 (16.3)

8 (18.6)

   

most days

n (%)

3 (7.0)

4 (9.3)

3 (7.0)

   

mean score

2.67

2.74

2.93

 Which size of bottle do you prefer?

large

n (%)

33 (76.7)

34 (79.1)

33 (76.7)

p = 1.000

p = 1.000

p = 1.000

small

n (%)

10 (23.3)

9 (20.9)

10 (23.3)

  1. **: not recorded for 1 participant
  2. *: p < 0.05
  3. ‡: Average times compound left – Wilcoxon matched-pairs rank sum test; Which size of bottle do you prefer – McNemar test