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Table 2 The risk of diabetes in later life following exposure to famine using different control groups

From: The association between fetal-stage exposure to the China famine and risk of diabetes mellitus in adulthood: results from the China health and retirement longitudinal study

Fetal-exposed group

Control groups

OR(95%CI)

No. cases/ sample size

Mean age (years)

Control groups

No. cases/ sample size

Mean age (years)

Total

113/832

51.8 ± 0.7

Non-exposed

139/1536

48.8 ± 0.6

1.58 (1.21–2.06)**

Infant-exposed

66/519

54.0 ± 0.5

0.92 (0.66–1.27)

Preschool-exposed

135/1251

55.5 ± 0.4

0.77 (0.59–1.01)

Age balanced

340/3306

52.2 ± 3.2

1.37 (1.09–1.72)**

Severe area

57/471

51.8 ± 0.7

Non-exposed

75/1010

48.8 ± 0.7

1.70 (1.18–2.45)**

Infant-exposed

44/343

54.0 ± 0.5

1.05 (0.69–1.61)

Preschool-exposed

86/819

55.5 ± 0.5

0.87 (0.61–1.25)

Age balanced

205/2172

52.2 ± 3.2

1.33 (0.97–1.82)

Less severe area

56/361

51.9 ± 0.7

Non-exposed

64/526

48.9 ± 0.7

1.33 (0.90–1.96)

Infant-exposed

22/176

54.0 ± 0.5

0.77 (0.45–1.31)

Preschool-exposed

49/432

55.5 ± 0.5

0.66 (0.43–1.01)

Age balanced

135/1134

52.2 ± 3.2

1.36 (0.97–1.91)

Male

55/393

51.9 ± 0.7

Non-exposed

72/733

48.9 ± 0.7

1.51 (1.03–2.20)*

Infant-exposed

32/278

54.0 ± 0.5

0.76 (0.47–1.24)

Preschool-exposed

62/636

55.5 ± 0.5

0.66 (0.44–0.97)*

Age balanced

166/1647

52.3 ± 3.2

1.47 (1.05–2.04)*

Female

58/439

51.8 ± 0.6

Non-exposed

67/803

48.8 ± 0.7

1.72 (1.18–2.50)**

Infant-exposed

34/241

54.0 ± 0.5

1.01 (0.63–1.60)

Preschool-exposed

73/615

55.5 ± 0.5

0.86 (0.59–1.26)

Age balanced

174/1659

52.0 ± 3.2

1.35 (0.98–1.86)

BMI < 24 kg/m2

43/423

51.8 ± 0.7

Non-exposed

56/807

48.8 ± 0.7

1.51 (0.99–2.29)

Infant-exposed

25/285

54.0 ± 0.5

0.87 (0.52–1.47)

Preschool-exposed

58/701

55.5 ± 0.5

0.84 (0.55–1.29)

Age balanced

139/1793

52.3 ± 3.2

1.34 (0.93–1.92)

BMI ≥ 24 kg/m2

70/409

51.9 ± 0.7

Non-exposed

83/729

48.8 ± 0.7

1.64 (1.16–2.31)**

Infant-exposed

41/234

54.0 ± 0.5

1.00 (0.65–1.53)

Preschool-exposed

77/550

55.5 ± 0.5

0.75 (0.52–1.07)

Age balanced

201/1513

52.0 ± 3.2

1.38 (1.02–1.86)*

  1. Abbreviations: OR odds ratio, CI confidence interval, NO. numbers
  2. All the analysis adjusted for gender, BMI, smoking status, drinking status, physical activity level, the highest education attainments of participants and their parents. * P < 0.05; ** P < 0.01