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Table 2 Clinical characteristics of inpatient drug-detoxification hospitalizations for patients aged≥12 years: 2003–2011 Nationwide Inpatient Samples

From: National trends and characteristics of inpatient detoxification for drug use disorders in the United States

Year Overall (2003–2011) 2003 2011 p value
Sample size, unweighted N 271,403 27,626 28,692
Weighted column, % % (95% CI) % (95% CI) % (95% CI)
Any-listed diagnosis
 Any drug use disorder 99.13 (98.96–99.28) 99.12 (98.82–99.35) 99.18 (98.71–99.48) 0.811
  Drug withdrawal 47.45 (42.85–52.09) 34.71 (23.76–47.56) 52.67 (41.57–63.52) 0.037
  Opioid use disorders 74.83 (72.70–76.85) 72.37 (63.93–79.47) 75.60 (68.64–81.43) 0.529
  Stimulant use disordersa 30.06 (27.63–32.61) 25.27 (19.71–31.79) 28.62 (22.89–35.14) 0.447
  Sedative use disorders 13.21 (11.99–14.52) 9.65 (7.27–12.69) 17.74 (13.28–23.31) 0.003
  Cannabis use disorders 12.14 (11.09–13.28) 10.19 (7.40–13.89) 14.26 (11.48–17.57) 0.081
  Other drug-related disordersb 11.87 (10.75–13.08) 12.90 (9.83–16.76) 11.08 (8.66–14.07) 0.409
 Alcohol use disorders 42.37 (39.41–45.38) 35.68 (29.05–42.90) 41.32 (32.54–50.69) 0.334
 Any non-addiction mental health disorder 47.93 (45.29–50.59) 43.16 (35.30–51.38) 58.98 (51.82–65.78) 0.004
  Mood disorders 38.35 (36.08–40.67) 34.66 (28.25–41.67) 46.42 (40.39–52.55) 0.013
  Schizophrenic/psychotic/ delusional disorders 3.94 (3.58–4.32) 3.35 (2.49–4.48) 5.19 (3.74–7.15) 0.048
  Anxiety disorders 10.82 (9.89–11.81) 8.17 (6.53–10.18) 17.38 (13.90–21.53) < 0.001
  Adjustment disorders 0.95 (0.79–1.13) 1.09 (0.79–1.50) 1.26 (0.51–3.08) 0.761
  Personality/impulse-control/disruptive behavior disorders 7.12 (6.29–8.04) 7.39 (5.55–9.78) 7.81 (5.74–10.54) 0.795
Primary diagnosis
 Any drug use disorder 71.26 (68.79–73.61) 71.73 (64.93–77.67) 64.53 (55.84–72.35) 0.175
  Drug withdrawal 33.68 (29.28–38.38) 24.60 (14.85–37.89) 35.37 (24.36–48.19) 0.214
  Opioid use disorders 27.27 (24.12–30.66) 36.95 (25.52–50.06) 20.51 (15.07–27.29) 0.013
  Stimulant use disordersa 5.45 (3.95–7.48) 5.16 (3.38–7.80) 4.38 (2.18–8.61) 0.688
  Sedative use disorders 1.38 (1.15–1.67) 1.21 (0.85–1.71) 1.68 (1.05–2.68) 0.266
  Cannabis use disorders 0.34 (0.23–0.49) 0.54 (0.18–1.61) 0.31 (0.12–0.76) 0.443
  Other drug-related disordersb 3.14 (2.68–3.67) 3.27 (2.39–4.47) 2.28 (1.63–3.18) 0.119
 Alcohol use disorders 12.45 (11.07–13.96) 11.53 (8.66–15.20) 15.70 (10.32–23.16) 0.223
 Any non-addiction mental health disorder 11.07 (9.60–12.72) 11.83 (8.68–15.92) 15.08 (9.90–22.80) 0.351
  Mood disorders 9.22 (8.00–10.60) 9.67 (7.03–13.16) 12.43 (8.37–18.05) 0.323
  Schizophrenic/psychotic/ delusional disorders 1.21 (1.01–1.45) 1.41 (0.95–2.09) 1.37 (0.82–2.26) 0.922
  Anxiety disorders 0.26 (0.19–0.36) 0.29 (0.15–0.59) 0.54 (0.16–1.85) 0.391
  Adjustment disorders 0.30 (0.20–0.44) 0.37 (0.22–0.62) 0.70 (0.16–2.98) 0.414
  Personality/impulse-control/disruptive behavior disorders 0.08 (0.05–0.15) 0.08 (0.04–0.16) 0.05 (0.02–0.14) 0.377
Secondary diagnosis
 Any drug use disorder 80.16 (77.10–82.90) 68.08 (57.56–77.03) 87.04 (81.71–90.99) < 0.001
  Drug withdrawal 13.77 (11.97–15.80) 10.11 (7.14–14.15) 17.33 (12.10–24.19) 0.030
  Opioid use disorders 47.73 (43.88–51.60) 35.59 (25.86–46.67) 55.25 (45.23–64.86) 0.009
  Stimulant use disordersa 24.79 (23.05–26.62) 20.41 (16.28–25.27) 24.35 (19.77–29.60) 0.246
  Sedative use disorders 11.83 (10.72–13.04) 8.44 (6.25–11.32) 16.07 (12.13–20.99) 0.002
  Cannabis use disorders 11.81 (10.81–12.89) 9.66 (7.15–12.93) 13.95 (11.29–17.12) 0.044
  Other drug-related disordersb 9.12 (8.30–10.00) 10.04 (7.53–13.26) 9.11 (7.09–11.64) 0.615
 Alcohol use disorders 36.12 (33.34–38.99) 29.44 (23.79–35.81) 33.63 (26.96–41.04) 0.375
 Any non-addiction mental health disorder 41.38 (39.24–43.55) 35.40 (29.13–42.22) 50.67 (44.93–56.40) 0.001
  Mood disorders 29.74 (28.08–31.45) 25.47 (20.90–30.65) 34.82 (30.19–39.77) 0.008
  Schizophrenic/psychotic/ delusional disorders 2.81 (2.53–3.13) 1.99 (1.47–2.69) 4.00 (2.75–5.79) 0.004
  Anxiety disorders 10.60 (9.70–11.57) 7.90 (6.31–9.85) 16.98 (13.68–20.88) < 0.001
  Adjustment disorders 0.65 (0.56–0.75) 0.72 (0.48–1.07) 0.57 (0.40–0.80) 0.378
  Personality/impulse-control/disruptive behavior disorders 7.07 (6.25–7.98) 7.33 (5.50–9.71) 7.77 (5.71–10.50) 0.785
  1. CI confidence interval
  2. We reduced the significant level to 0.01 due to a relatively large sample. Boldface: The estimate in 2003 in the category differed from the estimate in 2011 (p < 0.01)
  3. aStimulant included cocaine and amphetamine
  4. bOther drug-related disorders included drugs other than listed in the table defined by ICD-9-CM