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Table 3 Differences in pooled mean costs and effects

From: Cost-effectiveness of a blended physiotherapy intervention compared to usual physiotherapy in patients with hip and/or knee osteoarthritis: a cluster randomized controlled trial

Analysis

N e-Exercise

N Usual PT

Outcome

Ī”C (95% CI) In euroā€™s

Ī”E (95% CI) In points

ICER Euro/point

Distribution CE-plane (%)

Ā Ā Ā Ā Ā Ā Ā 

NEa

SEb

SWc

NWd

Main analysis 1:

109

99

QALYs (0ā€“1)

āˆ’529 (āˆ’ā€‰2265 to 1268)

0.01 (āˆ’ā€‰0.03 to 0.04)

āˆ’52,900

17.8

42.1

23.2

16.9

Total costs and imputed dataset

109

99

Physical functioning (0ā€“100)

āˆ’529 (āˆ’2265 to 1268)

1.49 (āˆ’4.70 to 7.69)

āˆ’355

20.5

44.7

20.6

14.2

109

99

Physical activity (min/day)

āˆ’529 (āˆ’2265 to 1268)

āˆ’3.46 (āˆ’11.66 to 4.73)

153

7.7

9.4

55.9

27.0

Main analysis 2:

109

99

QALYs (0ā€“1)

āˆ’792 (āˆ’ā€‰2101 to 440)

0.01 (āˆ’0.03 to 0.04)

āˆ’79,200

13.5

46.4

33.4

6.7

Healthcare costs and imputed dataset

109

99

Physical functioning (0ā€“100)

āˆ’792 (āˆ’2101 to 440)

1.49 (āˆ’4.70 to 7.69)

āˆ’532

14.4

50.7

29.2

5.7

109

99

Physical activity (min/day)

āˆ’792 (āˆ’2101 to 440)

āˆ’3.46 (āˆ’11.66 to 4.73)

229

5.2

11.9

67.9

15.0

Sensitivity analysis 1:

42

36

QALYs (0ā€“1)

2211 (701 to 3722)

āˆ’0.00 (āˆ’0.03 to 0.03)

āˆ’22,110

34.8

0.1

0.1

65.0

Complete cases

42

36

Physical functioning (0ā€“100)

2211 (701 to 3722)

āˆ’2.15 (āˆ’7.50 to 3.20)

āˆ’1.028

18.4

0.0

0.2

81.4

42

36

Physical activity (min/day)

2211 (701 to 3722)

āˆ’1.95 (āˆ’7.43 to 3.53)

āˆ’ā€‰1.134

22.0

0.0

0.2

77.8

Sensitivity analysis 2:

39

99

QALYs (0ā€“1)

āˆ’ā€‰592 (āˆ’ā€‰2719 to 1603)

0.02 (āˆ’0.01 to 0.06)

āˆ’ā€‰29,600

29.0

65.6

1.4

4.0

Per-protocol and imputed dataset

39

99

Physical functioning (0ā€“100)

āˆ’592 (āˆ’2719 to 1603)

4.10 (āˆ’1.56 to 9.77)

āˆ’ā€‰144

30.7

66.1

0.8

2.4

39

99

Physical activity (min/day)

āˆ’592 (āˆ’2719 to 1603)

āˆ’1.79 (āˆ’ā€‰8.72 to 5.13)

331

12.8

18.3

48.7

20.2

  1. CI confidence interval, C costs, CE-plane cost-effectiveness plane, E effects, ICER incremental cost-effectiveness Ratio costs are expressed in 2015 Euros
  2. aThe northeast quadrant of the CE plane, indicating that e-Exercise is more effective and more costly than usual physiotherapy
  3. bThe southeast quadrant of the CE plane, indicating that e-Exercise is more effective and less costly than usual physiotherapy
  4. cThe northwest quadrant of the CE plane, indicating that e-Exercise is less effective and more costly than usual physiotherapy
  5. dThe southwest quadrant of the CE plane, indicating that e-Exercise is less effective and less costly than usual physiotherapy
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BMC Public Health

ISSN: 1471-2458

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