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Table 4 General knowledge (percentage with correct answer) on HPV and cervical cancer among vaccinated and unvaccinated participants on the first and last rounds

From: Changes in (risk) behavior and HPV knowledge among Dutch girls eligible for HPV vaccination: an observational cohort study

  Round 1a Round 5   
Category n (%) n (%) p-value Mean difference (+ 95% CI)
General knowledge score (mean 95%CI)
 Unvaccinated 4.25 (4.14–4.36) 4.70 (4.54–4.87) < 0.01 Ref
 Vaccinated 4.29 (4.21–4.37) 4.92 (4.80–5.03) < 0.01 0.11 (− 0.02–0.23)
HPV infections are easily treatable (No)
 Unvaccinated 142 (14) 96 (20)   
 Vaccinated 284 (15) 279 (27)   
HPV infections are rare (No)
 Unvaccinated 428 (42) 232 (48)   
 Vaccinated 882 (46) 554 (53)   
An HPV infection always leads to cervical cancer (No)
 Unvaccinated 690 (68) 389 (80)   
Vaccinated 1294 (64) 844 (81)   
Cervical cancer is always fatal (No)
 Unvaccinated 835 (82) 427 (88)   
 Vaccinated 1579 (82) 923 (89)   
Cervical cancer is easily treatable (No)  
 Unvaccinated 178 (18) 108 (22)   
 Vaccinated 408 (21) 273 (26)   
Cervical cancer is a common disease (No)
 Unvaccinated 237 (23) 116 (24)   
 Vaccinated 334 (17) 238 (23)   
If you have unprotected sex, you are at high risk of an HPV infection (Yes)
 Unvaccinated 732 (72) 345 (71)   
 Vaccinated 1411 (74) 782 (75)   
An HPV infection is a risk for cervical cancer (Yes)
 Unvaccinated 815 (80) 400 (82)   
 Vaccinated 1555 (81) 888 (85)   
An HPV infection can cause genital warts (Yes)
 Unvaccinated 193 (19) 134 (28)   
 Vaccinated 389 (20) 274 (26)   
An HPV infection usually disappears on its own (Yes)
 Unvaccinated 56 (6) 42 (9)   
 Vaccinated 80 (4) 61 (6)   
  1. Questions regarding general knowledge were only incorporated in the questionnaires of round one (first) and round five (last). The p-values of vaccinated and unvaccinated girls indicate whether the knowledge changed over time within these groups
  2. aPreviously published by Mollers et al. [17]