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Table 1 Factors associated with medication adherence among newly treated HIV-infected patients

From: Medication adherence to antiretroviral therapy among newly treated people living with HIV

Characteristics

Total N(%)

Good adherence n(%)

t/χ2

OR(95%CI)

Socio-demographic characteristics

 Sex

  

0.702

  Male

184 (88.9)

156 (84.8)

  

  Female

23 (11.1)

21 (91.3)

  

 Age (years)

  

0.347

  18–28

79 (38.2)

69 (87.3)

  

   ≥ 28

128 (61.8)

108 (84.4)

  

Household registration

  

0.179

 Rural

104 (50.2)

90 (86.5)

  

 Urban

103 (49.8)

87 (84.5)

  

Education level

  

0.418

 Senior or lower

127 (61.4)

107 (84.5)

  

 College or higher

80 (38.6)

70 (87.5)

  

Marital status

  

0.004

 Single

103 (49.8)

88 (85.4)

  

 Divorced/Widowed

34 (16.4)

29 (85.3)

  

 Married

70 (33.8)

60 (85.7)

  

Monthly income(yuan)*

  

0.051

  ≤ 3500

107 (53.2)

91 (85.0)

  

  > 3500

94 (46.8)

81 (86.2)

  

Living alone

  

0.032

 Yes

51 (24.6)

44 (86.3)

  

 No

156 (75.4)

133 (85.3)

  

Employment status

  

1.525

 Unemployed

76 (36.7)

68 (89.5)

  

 Employed

131 (63.3)

109 (83.2)

  

HIV-related information

 Infection route

  

2.876

  Blood/Uncertain

6 (2.9)

6 (100.0)

  

  Homosexual transmission

98 (47.3)

80 (81.6)

  

  Heterosexual transmission

103 (49.8)

91 (88.3)

  

 Disclosure of HIV status

  

2.381

 

  No

71 (34.3)

57 (80.3)

 

2.62 (1.06–6.50)*

  Yes

136 (65.7)

120 (88.2)

 

Ref

 CD4 count(mm3)*

   ≤ 350

147 (71.4)

124 (84.4)

0.484

   > 350

59 (28.6)

52 (88.1)

  

 AIDS-related symptoms

  

9.017**

  No

127 (61.4)

116 (91.3)

  

  Yes

80 (38.6)

61 (76.2)

  

Psychosocial factors

 Depressive symptoms

  

20.248**

 

  Yes

139 (67.1)

113 (81.2)

 

5.95 (2.34–15.11)*

  No

68 (32.9)

64 (94.1)

 

Ref

 Anxiety symptoms

  

12.279**

  Yes

133 (64.3)

109 (81.9)

  

  No

74 (35.7)

68 (91.9)

  

Antiviral treatment information

  

 Therapeutic regimen#

4.2

  AZT + 3TC + EFV

30 (14.5)

26 (86.7)

  

  Othera

25 (12.1)

18 (72.0)

  

  TDF + 3TC + EFV

152 (73.4)

133 (87.5)

  

 Side effects

  

0.235

  Yes

144 (69.6)

122 (84.7)

  

  No

63 (30.4)

55 (87.3)

  

 Medication reminders*

  

0.772

  0

3 (1.7)

2 (66.7)

  

  1

151 (85.3)

131 (86.8)

  

   ≥ 2

23 (13.0)

17 (73.9)

  

 Knowledge of ART (M ± SD)

 

1.68 ± 0.90

1.107

 Satisfaction with medical services (M ± SD)

 

9.38 ± 1.11

2.976

  1. *P < 0.05; **P < 0.01
  2. OR Odds ratio; —:not included in the final model
  3. #TDF Tiroflove, 3TC Lamivudine, EFV Efavirenz, AZT Zidovudine, NVP Nevirapine, LPV/r Lopinavir/Ritonavir
  4. aAZT + 3TC + NVP, AZT + 3TC + LPV/r, 3TC + NVP + TDF;
  5. Ref Reference group; * data missing