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Table 1 Factors associated with medication adherence among newly treated HIV-infected patients

From: Medication adherence to antiretroviral therapy among newly treated people living with HIV

Characteristics Total N(%) Good adherence n(%) t/χ2 OR(95%CI)
Socio-demographic characteristics
 Sex    0.702
  Male 184 (88.9) 156 (84.8)   
  Female 23 (11.1) 21 (91.3)   
 Age (years)    0.347
  18–28 79 (38.2) 69 (87.3)   
   ≥ 28 128 (61.8) 108 (84.4)   
Household registration    0.179
 Rural 104 (50.2) 90 (86.5)   
 Urban 103 (49.8) 87 (84.5)   
Education level    0.418
 Senior or lower 127 (61.4) 107 (84.5)   
 College or higher 80 (38.6) 70 (87.5)   
Marital status    0.004
 Single 103 (49.8) 88 (85.4)   
 Divorced/Widowed 34 (16.4) 29 (85.3)   
 Married 70 (33.8) 60 (85.7)   
Monthly income(yuan)*    0.051
  ≤ 3500 107 (53.2) 91 (85.0)   
  > 3500 94 (46.8) 81 (86.2)   
Living alone    0.032
 Yes 51 (24.6) 44 (86.3)   
 No 156 (75.4) 133 (85.3)   
Employment status    1.525
 Unemployed 76 (36.7) 68 (89.5)   
 Employed 131 (63.3) 109 (83.2)   
HIV-related information
 Infection route    2.876
  Blood/Uncertain 6 (2.9) 6 (100.0)   
  Homosexual transmission 98 (47.3) 80 (81.6)   
  Heterosexual transmission 103 (49.8) 91 (88.3)   
 Disclosure of HIV status    2.381  
  No 71 (34.3) 57 (80.3)   2.62 (1.06–6.50)*
  Yes 136 (65.7) 120 (88.2)   Ref
 CD4 count(mm3)*
   ≤ 350 147 (71.4) 124 (84.4) 0.484
   > 350 59 (28.6) 52 (88.1)   
 AIDS-related symptoms    9.017**
  No 127 (61.4) 116 (91.3)   
  Yes 80 (38.6) 61 (76.2)   
Psychosocial factors
 Depressive symptoms    20.248**  
  Yes 139 (67.1) 113 (81.2)   5.95 (2.34–15.11)*
  No 68 (32.9) 64 (94.1)   Ref
 Anxiety symptoms    12.279**
  Yes 133 (64.3) 109 (81.9)   
  No 74 (35.7) 68 (91.9)   
Antiviral treatment information   
 Therapeutic regimen# 4.2
  AZT + 3TC + EFV 30 (14.5) 26 (86.7)   
  Othera 25 (12.1) 18 (72.0)   
  TDF + 3TC + EFV 152 (73.4) 133 (87.5)   
 Side effects    0.235
  Yes 144 (69.6) 122 (84.7)   
  No 63 (30.4) 55 (87.3)   
 Medication reminders*    0.772
  0 3 (1.7) 2 (66.7)   
  1 151 (85.3) 131 (86.8)   
   ≥ 2 23 (13.0) 17 (73.9)   
 Knowledge of ART (M ± SD)   1.68 ± 0.90 1.107
 Satisfaction with medical services (M ± SD)   9.38 ± 1.11 2.976
  1. *P < 0.05; **P < 0.01
  2. OR Odds ratio; —:not included in the final model
  3. #TDF Tiroflove, 3TC Lamivudine, EFV Efavirenz, AZT Zidovudine, NVP Nevirapine, LPV/r Lopinavir/Ritonavir
  4. aAZT + 3TC + NVP, AZT + 3TC + LPV/r, 3TC + NVP + TDF;
  5. Ref Reference group; * data missing