Table 1 Definitions of transmission parameters
From: High-resolution epidemic simulation using within-host infection and contact data
| Â | Measure | Definition |
|---|---|---|
A | Incubation period | the interval between exposure to a pathogen and initial occurrence of symptoms [79] was defined as from the infection time to the first time the viral load crosses over the detectable threshold (Fig. 2). |
B | Time from symptom onset to recovery [79] | defined as the interval between the first day of detectable viral load and the first day the viral load becomes undetectable (Fig. 2). |
C | Time from symptom onset to death [79] | defined as the interval between the first day with detectable viral load and the day the area under the viral load curve (AUC) crosses the reference threshold AUC7 (Fig. 2). |
D | Basic reproductive number (R0) | calculated based on the network of infected subjects at the end of an epidemic in an initially susceptible population. In a network model, this equals the mean degree distribution of the infected network, considering a directed network without loops (e.g., Fig. 5). The R0 by age-group was also calculated in the same fashion based on the assigned age-attribute. In epidemics with intervention or when the population is not fully susceptible, the R0 is called the effective reproduction number (Re). |
E | Final infected fraction | the proportion of infected nodes at the end of an epidemic simulation. |
F | Case-fatality rate | the proportion of nodes who died as a result of EBOV infection counted at the end of an epidemic simulation. |