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Table 5 Multiple comorbidities associated with global self-rated health stratified by residential location and sex

From: Association between multiple comorbidities and self-rated health status in middle-aged and elderly Chinese: the China Kadoorie Biobank study

 

Administrative region

P for interaction

Sex

P for interaction

Rural

Urban

Male

Female

OR

95% CI

OR

95% CI

OR

95% CI

OR

95% CI

Cardiometabolic diseases

 Coronary heart disease

2.75

2.55, 2.96

2.34

2.22, 2.46

< 0.001

2.57

2.41, 2.75

2.50

2.37, 2.64

0.12

 Rheumatic heart disease

3.63

2.82, 4.67

2.62

2.03, 3.37

0.07

4.41

2.99, 6.49

2.86

2.33, 3.50

0.07

 Stroke

2.92

2.67, 3.20

2.69

2.50, 2.89

0.02

3.16

2.93, 3.40

2.69

2.46, 2.93

0.23

 Hypertension

1.15

1.13, 1.17

1.22

1.20, 1.25

0.006

1.24

1.22, 1.27

1.24

1.22, 1.27

0.01

 Diabetes

1.64

1.57, 1.71

1.83

1.77, 1.90

0.007

1.90

1.82, 1.98

1.69

1.63, 1.75

0.006

Respiratory diseases

 Tuberculosis

1.60

1.48, 1.73

1.37

1.28, 1.47

< 0.001

1.55

1.45, 1.66

1.40

1.30, 1.51

0.31

 Emphysema/bronchitis

2.87

2.71, 3.05

1.81

1.70, 1.92

< 0.001

2.49

2.34, 2.64

2.45

2.31, 2.60

0.99

 Asthma

1.89

1.63, 2.20

2.16

1.93, 2.41

0.69

2.05

1.78, 2.35

2.05

1.81, 2.31

0.81

Musculoskeletal diseases

 Fracture

1.09

1.06, 1.13

1.01

0.98, 1.04

< 0.001

1.09

1.05, 1.12

1.10

1.07, 1.14

0.88

 Rheumatoid arthritis

1.82

1.70, 1.94

1.91

1.80, 2.03

0.80

1.71

1.58, 1.85

1.87

1.77, 1.97

0.008

Mental diseases

 Depressive Symptoms

2.50

2.24, 2.78

2.49

2.16, 2.89

0.53

2.60

2.22, 3.05

2.70

2.44, 3.00

0.98

 Psychiatric disorders

1.94

1.68, 2.24

1.88

1.62, 2.19

0.68

2.40

1.97, 2.93

2.04

1.79, 2.31

0.10

 Neurasthenia

2.00

1.82, 2.19

1.91

1.75, 2.07

0.22

1.90

1.70, 2.13

2.23

2.07, 2.41

0.005

Digestive diseases

 Cirrhosis/chronic hepatitis

1.56

1.45, 1.68

1.89

1.74, 2.06

< 0.001

1.70

1.59, 1.83

1.58

1.45, 1.73

0.07

 Peptic ulcer

1.80

1.72, 1.89

1.61

1.55, 1.68

< 0.001

1.57

1.50, 1.63

1.89

1.80, 1.99

< 0.001

 Gallstone/gallbladder disease

1.57

1.51, 1.62

1.37

1.32, 1.42

< 0.001

1.52

1.45, 1.60

1.61

1.56, 1.66

0.004

Cancer

2.09

1.81, 2.40

2.71

2.37, 3.09

0.01

2.99

2.54, 3.51

2.31

2.05, 2.61

0.02

Other diseases

 Kidney disease

1.75

1.63, 1.88

1.40

1.30, 1.51

< 0.001

1.50

1.38, 1.63

1.72

1.61, 1.84

< 0.001

 Head injury

1.26

1.17, 1.37

1.20

1.11, 1.30

0.10

1.19

1.11, 1.28

1.20

1.09, 1.31

0.81

  1. Abbreviations: CI confidence intervals, OR odds ratio
  2. Odds ratios (95% CI) were calculated after adjustment of age, sex, study location, marital status, household income, education level, occupation, alcohol drinking, cigarette smoking, physical activity, BMI, family history of five diseases (stroke, heart attack, diabetes, mental disorders and cancer) and all comorbidities, except for the stratified variable in the corresponding stratified analysis