Table 1 Patient demographics and liver disease factors predicting the presence or absence of familial clustering of HCV using univariate logistic regression analysis
Parameters | Familial Clustering | OR | 95%CI | P value | ||
|---|---|---|---|---|---|---|
Yes n = 59 (%) | No n = 938(%) | L | U | |||
Gender | 0.846 | 0.500 | 1.432 | 0.534 | ||
Male | 30(50.8) | 516(55.0) | ||||
Female | 29(49.2) | 422(45.0) | ||||
Age, median years (Q1,Q3) | 43(37,53) | 46(37,56) | 0.990 | 0.971 | 1.010 | 0.338 |
Cirrhosis | 0.144 | 0.020 | 1.054 | 0.056 | ||
Yes | 1(1.7) | 100(10.7) | ||||
No | 58(98.3) | 838(89.3) | ||||
Diagnosis time, median months (Q1,Q3) | 5(1,24) | 3(1,28) | 1.002 | 0.998 | 1.007 | 0.280 |
Possible infected duration, median months (Q1,Q3) | 203(165,244) | 219(160,252) | 0.999 | 0.996 | 1.002 | 0.593 |
HCV RNA, median Log10IU/ml (Q1,Q3) | 6.06(5.17,6.55) | 6.07(5.37,6.53) | 1.030 | 0.788 | 1.347 | 0.826 |
Genotype | ||||||
1 | 23(39.0) | 559(59.6) | 1.000 | |||
2 | 23(39.0) | 217(23.1) | 2.576 | 1.415 | 4.688 | 0.002* |
3 | 6(10.2) | 85(9.1) | 1.716 | 0.679 | 4.335 | 0.254 |
6 | 5(8.5) | 58(6.2) | 2.095 | 0.768 | 5.719 | 0.149 |
Mixed | 2(3.4) | 19(2.0) | 2.558 | 0.562 | 11.645 | 0.224 |