|
HRIZ → M in prevalence ratioa
|
Intra-observer TEMb
|
Prevalence ratio c
|
Sensitivity (%)
|
Specificity (%)
|
Expected observed prevalence ratio
|
Proportion of false positives (%)
|
|---|
|
1
|
0.24
|
1.00
|
85.1
|
99.4
|
1.00
|
22.6
|
|
5
|
0.24
|
1.23
|
85.1
|
99.4
|
1.19
|
15.6
|
|
10
|
0.24
|
1.38
|
85.1
|
99.4
|
1.33
|
11.1
|
|
15
|
0.24
|
1.47
|
85.1
|
99.4
|
1.41
|
8.6
|
|
1
|
0.71
|
1.00
|
91.8
|
97.2
|
1.00
|
56.6
|
|
5
|
0.71
|
1.23
|
91.8
|
97.2
|
1.12
|
45.2
|
|
10
|
0.71
|
1.38
|
91.8
|
97.2
|
1.22
|
35.9
|
|
15
|
0.71
|
1.47
|
91.8
|
97.2
|
1.30
|
29.6
|
- a HRIZ → M: Hypothetical relative increase in the prevalence of microcephaly
- b TEM: Intraobserver technical error of measurement of head circumference
- c Prevalence ratio of microcephaly (outbreak vs non-outbreak period) under perfect diagnostic sensitivity and specificity
