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Table 3 Prevalence of potential inappropriate/teratogen prescriptions during pregnancy according to trimesters at risk and ATC groups

From: Drug prescribing during pregnancy in a central region of Italy, 2008-2012

Potential inappropriate drugs ATC Trimester at risk Na %
Total    44,303 23.33
Progestogens G03D 1-2 38,146 20.09
Glucocorticoids for systemic use H02AB 1 4458 2.35
Propionic acid derivates (Ibuprofen, Naproxen, Ketoprofen) M01AE01-03 1-3 2495 1.31
Anti-inflammatory and antirheumatic M01AX 1-3 2203 1.16
Acetic acid derivatives and related substances (excluding Indomethacin) M01AB (exc M01AB01) 1-3 1461 0.77
Oxicams M01 AC 1-3 200 0.11
Bile acid sequestrants C10AC 1-3 191 0.10
Coxib M01AH 1-2 40 0.02
Antigonadotropins and similar agents G03XA 1-2 8 0.00
Indomethacin M01AB01 1-2 8 0.00
Ezetimibe C10AX09 1-3 1 0.00
Nicotinic acid and its derivatives C10AD 1-3 0 0.00
Known or potential teratogen drugs ATC Trimester at risk Na %
Total    1420 0.78
ACE-inhibitors, ARBs or combinations C09 2-3 508 0.27
HMG-CoA reductase inhibitors (statins) C10AA,C10B 1-3 297 0.16
Barbiturates and derivatives N03AA 1-3 199 0.10
Fatty acid derivatives N03AG 1-3 177 0.09
Benzodiazepine derivatives N03AE 1-3 132 0.07
Tetracycline J01AA 3 91 0.05
Imidazole and its derivatives (Thiamazole) H03BB02 1 48 0.03
Triazole and its derivatives (Fluconazole) J02AC01 1 16 0.01
Lithium N05AN01 1-3 16 0.01
Vitamin K antagonists B01AA 1-3 13 0.01
Anti-arrhythmic drugs class III (Amiodarone) C01BD01 1-3 9 0.00
Retinoids for acne treatment D10BA01 1 4 0.00
Penicillamine and similar agents M01CC 1-3 3 0.00
Retinoids for psoriasis treatment D05BB 1-3 2 0.00
  1. awomen with at least one prescription