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Table 4 Showing the performance measures of Kato-Katz by each survey round with POC-CCA as the gold standard

From: Comparing the performance of circulating cathodic antigen and Kato-Katz techniques in evaluating Schistosoma mansoni infection in areas with low prevalence in selected counties of Kenya: a cross-sectional study

Treatment round

Sensitivity %(95% CI)

Specificity %(95% CI)

LR+ %(95% CI)

LR− %(95% CI)

PPV %(95% CI)

NPV %(95% CI)

Kappa index (Agreement %)

Pre-treatment

12.5 (9.7–15.8)

97.9 (97.0–98.6)

6.0 (3.8–9.3)

0.9 (0.9–0.9)

69.0 (58.1–78.5)

75.0 (72.8–77.0)

0.14 (74.7%)

Post-treatment

5.2 (3.2–7.9)

99.5 (99.0–99.8)

10.6 (4.5–24.8)

1.0 (0.9–1.0)

74.1 (53.7–88.9)

79.5 (77.6–81.4)

0.07 (79.4%)

Overall

P-value**

9.3 (7.4–11.4)

Χ2m = 782.0, p < 0.001

98.7 (98.2–99.1)

Χ2m = 34.0, p < 0.001

7.4 (5.0–10.92)

-

0.9 (0.9–0.9)

-

70.2 (60.9–78.4)

-

77.3 (75.9–78.7)

-

0.11 (77.1%)

Z = 11.6, p < 0.001

  1. PPV positive predictive value, NPV negative predictive value, LR+ positive likelihood ratio, LR− negative likelihood ratio
  2. **Obtained from McNemar’s chi-square (Χ2m) test (sensitivity & specificity) / Weighted generalized score chi-square test (PPV & NPV)