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Table 1 Study; Country Study type; Setting; Conditions; Diagnosis tool; Number of participants; Age; and Sex

From: A scoping study of interventions to increase the uptake of physical activity (PA) amongst individuals with mild-to-moderate depression (MMD)

Author Country Study type Setting Conditions (%) Provided, whenever available, if an interventions was delivered to a mixed clinical group Diagnosis tool Number of participants Age Sex
Forsyth et al., 2009 [64] Australia Pilot (feasibility) RCT Primary Care a) Depression (51%)
b) Anxiety (19%)
c) Mixed anxiety-depression disorder (30%)
Participants’ mean BMI = 29.7 kg/m2
The Depression Anxiety Stress Scale
DASS-21
At baseline = 25; but only 18 patients completed an initial assessment
At week 12 = 5
Age range: 19–73 At baseline:
Male = 9
Female = 16
Mailey et al., 2010 [25] USA Pilot RCT Community and University-based Healthcare Services a) Depression
b) Anxiety
The Beck’s Depression Inventory (BDI) Intervention arm
At baseline = 26
At week 10 = 23
Control arm
At baseline = 25
At week 10 = 24
At baseline:
Intervention & Control Arms
= 25 yr (18–52 yr)
At baseline:
The sample (in both study arms) was primary female (68.1%)
Oeland et al., 2010 [31] Denmark RCT Primary Care a) Mild-to-moderate depression (MMD)
b) MMD recurrent
c) Anxiety
The Hamilton Depression Rating Scale (HAM-D) Intervention Arm
At baseline:
Total number of Pts = 27
[MMD (60%); MMD recurrent (18%); Anxiety (23%)]
At week 32:
Total number of Pts = 13 [condition-specific information - not provided]
Control Arm
Total number of Pts: 21
[MMD (43%); MMD recurrent (38%); Anxiety (20%)]
At week 32:
Total number of Pts = 15 [condition-specific information - not provided]
At baseline:
Intervention arm = 36 yr (18–52)
Control arm = 40 yr (20–67)
At baseline:
Intervention arm = 85/15
Control arm = 67/33
Pentecost et al., 2015 [32] UK Pilot RCT Primary Care: Improving Access to Psychological Therapies (IAPT) Services a) Mild Depression
b) Moderate Depression
c) Severe Depression
The Clinical Interview Schedule - Revised (CIS-R) & the Patient Health Questionnaire-9 (PHQ-9) Intervention 1 arm
At baseline:
(Behavioural activation plus physical activity promotion)
Mild depression = 6 (20%)
Moderate depression = 16 (53.3%)
Severe depression = 8 (26.7%)
At week 16:
Mild depression = 4 (13.3)
Moderate depression = 16 (53.3%)
Severe depression = 10 (33.3%)
Intervention 2 arm
(Behavioural activation)
At baseline:
Mild depression = 2 (9.1%)
Moderate depression = 2 (9.1%)
Severe depression = 1 (4.5%)
At week 16:
Mild depression = 1 (4.8%)
Moderate depression = 4 (19%)
Severe depression = 3 (14.3%)
At baseline:
Intervention 1 arm
18–30 yr, n = 6
31+ yr, n = 24
Intervention 2 arm
18–30 yr, n (%) = 6
31+ yr, n = 24
At baseline:
Intervention 1 arm
Male = 18
Female = 20
Intervention 2 arm
Male = 13
Female = 17
Piette et al., 2011 [26] USA RCT Various, a community-university-and VA healthcare system Comorbid moderate depression (Beck Depression Inventory scores ≥14) & diabetes The Beck’s Depression Inventory (BDI) Intervention arm
At baseline = 172
At 12 months = 145
Control arm
At baseline = 167
At 12 months = 146
At baseline:
Patients’ mean age was 56 yr
At baseline:
Male = 49%
Female = 51%
Suija et al., 2009 [27] Estonia RCT Primary Care Mild-to-moderate depression (MMD) The Composite International Diagnostic Interview (CIDI) Intervention arm (patients with depression)
At baseline = 48 randomised; 16 agreed to participate in the study
At week 24 = 4
Control arm (non-depressed patients)
At baseline = 58 randomised; 5 agreed to participate in the study
At week 24 = 5
At baseline:
18–29 yr, n = 7
40–59 yr, n = 5
≥60 yr, n = 1
At baseline:
Male = 1
Female = 15
Crone et al., 2008 [33] UK Quasi-experimental Primary Care Mental health group (4.6% of all study participants); this included:
a) Depression (61%)
b) Anxiety/loss of confidence (26%)
c) Stress/tension (13%)
Physical health:
Cardio-vascular disease, overweight, obesity, diabetes, musculoskeletal health, unfit/sedentary, or other
No information given At baseline:
Mental health = 134
Physical health = 2500
At 12 week or programme
completion:
Mental health = 29
Physical health = 935
At baseline:
Mental health group:
42 ± 14 yr
Physical health group:
51 ± 14 yr
At baseline:
Male = 36%
Female = 64%
Duda et al., 2014 [28] UK RCT Primary Care Mental health group:
a) Probable (Mild) Depression (18.9%)
b) Probable anxiety (34.8%)
Comorbidities:
Two or more factors for coronary heart disease (CHD), overweight, obesity, other long term conditions (LTCs), asthma, bronchitis, diabetes, those for whom regular PA may prevent the onset of osteoporosis, those with borderline hypertension.
The Hospital Anxiety and Depression Scale (HADS) Total No of participants:
347 (a sample of 494 participants was required to detect a difference in mean PA time across the intervention and control arms)
Intervention arm
At baseline = 184
At 6-month follow up = 82
Control arm
At baseline = 163
At week = 92
At baseline:
Intervention arm
< 30 yr, n = 19
30–49 yr, n = 76
50–64 yr, n = 64
≥65 yr, n = 25
Control arm
< 30 yr, n = 11
30–49 yr, n = 77
50–64 yr, n = 50
≥65 yr, n = 25
At baseline:
Intervention arm
Male = 45 (24.5%)
Female = 139 (75.5%)
Control arm
Male = 49 (30.1%)
Female = 114 (69.9%)
Littlecott et al., 2014 [29] UK RCT Primary Care Mental health (4%):
a) Depression
b) Anxiety
Physical health:
a) CHD risk factors
Both: Comorbid mental health and physical health
The Hospital Anxiety and Depression Scale (HADS) At baseline, 1080 participants were randomised to each trial arm
Intervention arm
At 12 months:
Mental health =19
CHD risk = 362
Control arm
At 12 months:
Mental health = 13
CHD risk = 339
At baseline:
16–44 yr, n = 191
45–59 yr, n = 303
≥60 yr, n 386
Condition-specific age data is not provided
At baseline:
Male = 316
Female = 590
Condition-specific sex data is not provided
Pomp et al., 2013 [30] Germany Quasi-experimental Orthopaedic rehabilitation Depression (10%)
Other health conditions - no information available
The Patient Health Questionnaire-9 (PHQ-9) Intervention arm
At baseline = 227
At week 6 = 132
Control arm
At baseline = 279
At week 6 = 229
The authors state that the control and intervention arms did not differ in terms of sex and age. No further details are provided. The authors state that the control and intervention arms did not differ in terms of sex and age. No further details are provided.