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Table 4 Age-adjusted prevalence of cardiovascular risk factors by sex and HbA1c-defined diabetes status among adults aged 20 years or older, 1988–2014a

From: Trends in cardiovascular risk factors among U.S. men and women with and without diabetes, 1988–2014

Risk actors by sex and diabetes status

NHANES 1988–1994

NHANES 1999–2002

NHANES 2003–2006

NHANES 2007–2010

NHANES 2011–2014

P Value for Linear Trend, 1988–1994 to 2011-2014b

P Value for Comparison of NHANES 2011–2014 and NHANES 1988–1994

Smoking (%)

 Non-diabetic Men

32.64 (30.48–34.80)

22.96 (20.64–25.27)

23.63 (21.42–25.83)

20.35 (18.10–22.61)

18.74 (15.86–21.63)

<.0001

−13.90 (−17.50 to −10.30)

 Diabetic Men

20.48 (15.50–25.46)

20.08 (15.12–25.04)

18.89 (13.38–24.41)

18.76 (14.97–22.55)

18.23 (10.70–25.75)

0.1560

−2.25 (−11.29 to 6.78)

 Non-diabetic Women

25.32 (23.55–27.09)

18.88 (16.96–20.81)

18.86 (16.90–20.83)

16.25 (14.34–18.16)

13.92 (11.95–15.90)

<.0001

−11.40 (−14.05 to −8.75)

 Diabetic Women

19.44 (14.95–23.93)

9.57 (6.33–12.81)

11.00 (6.85–15.15)

14.11 (10.27–17.94)

13.21 (7.83–18.59)

0.0501

−6.23 (−13.25 to 0.78)

Use of antihypertensive medications (%)

 Non-diabetic Men

9.03 (7.74–10.32)

15.16 (13.48–16.84)

20.02 (18.28–21.76)

21.07 (18.81–23.32)

20.98 (17.59–24.38)

<.0001

11.95 (8.33 to 15.58)

 Diabetic Men

31.32 (25.48–37.16)

45.67 (39.25–52.08)

55.49 (51.12–59.86)

54.54 (49.08–60.00)

62.19 (53.98–70.39)

<.0001

30.87 (20.79 to 40.95)

 Non-diabetic Women

12.45 (11.50–13.40)

19.87 (17.93–21.82)

21.64 (19.74–23.55)

23.09 (21.56–24.63)

23.90 (20.51–27.28)

<.0001

11.45 (7.93 to 14.96)

 Diabetic Women

41.68 (36.37–46.99)

59.86 (53.44–66.28)

65.60 (60.13–71.08)

70.62 (66.68–74.57)

64.53 (59.03–70.03)

<.0001

22.85 (15.20 to 30.50)

Use of Lipid-Lowering Medications (%)

 Non-diabetic Men

2.13 (1.62–2.64)

8.38 (7.16–9.61)

11.20 (9.91–12.50)

13.24 (11.70–14.79)

14.00 (11.12–16.88)

<.0001

11.87 (8.94 to 14.79)

 Diabetic Men

9.56 (5.86–13.27)

28.33 (24.28–32.39)

42.83 (36.78–48.88)

45.50 (42.02–48.98)

49.15 (41.97–56.33)

<.0001

39.59 (31.50 to 47.67)

 Non-diabetic Women

2.97 (2.28–3.66)

6.69 (5.75–7.63)

10.32 (8.75–11.89)

12.29 (11.10–13.47)

14.14 (11.19–17.10)

<.0001

11.17 (8.14 to 14.21)

 Diabetic Women

6.43 (4.01–8.86)

26.12 (19.86–32.38)

40.79 (34.63–46.94)

45.02 (39.76–50.28)

51.72 (43.41–60.03)

<.0001

45.29 (36.63 to 53.95)

Prevalence of achieving systolic/diastolic blood pressure < 130/80 mmHg (%)

 Non-diabetic Men

72.00 (69.80–74.20)

72.80 (70.59–75.01)

71.45 (69.66–73.25)

76.39 (74.61–78.17)

76.88 (73.96–79.80)

<.0001

4.88 (1.22 to 8.54)

 Diabetic Men

42.84 (35.58–50.10)

52.33 (47.70–56.96)

55.27 (47.10–63.43)

59.69 (55.58–63.81)

55.22 (45.02–65.42)

0.0018

12.38 (−0.15 to 24.91)

 Non-diabetic Women

76.39 (74.34–78.44)

72.04 (70.19–73.90)

75.85 (74.16–77.55)

79.15 (77.42–80.88)

78.49 (76.36–80.62)

<.0001

2.10 (−0.85 to 5.06)

 Diabetic Women

39.87 (34.57–45.18)

41.98 (35.16–48.81)

46.74 (41.14–52.34)

57.19 (53.18–61.20)

54.12 (47.65–60.58)

<.0001

14.25 (5.88 to 22.61)

Prevalence of achieving LDL-cholesterol <100 mg/dL (%)

 Non-diabetic Men

64.69 (62.55–66.83)

64.99 (62.72–67.27)

68.02 (66.23–69.81)

68.82 (67.10–70.54)

68.08 (64.45–71.71)

<.0001

3.39 (−0.82 to 7.60)

 Diabetic Men

68.23 (62.30–74.16)

77.81 (71.93–83.69)

78.18 (73.69–82.68)

79.29 (75.22–83.36)

76.98 (70.72–83.25)

0.0014

8.75 (0.12 to 17.39)

 Non-diabetic Women

66.42 (64.60–68.24)

68.06 (66.25–69.87)

70.97 (69.28–72.65)

68.87 (67.41–70.34)

68.01 (64.84–71.18)

0.0016

1.59 (−2.07 to 5.24)

 Diabetic Women

73.26 (67.97–78.55)

79.64 (74.13–85.14)

76.82 (70.86–82.78)

75.59 (71.87–79.32)

75.47 (70.81–80.13)

0.6815

2.21 (−4.85 to 9.26)

Prevalence of achieving HbA1c <7.0% (%)

 Diabetic Men

42.28 (36.06–48.50)

38.10 (33.12–43.08)

43.52 (38.05–48.99)

43.42 (38.21–48.63)

50.58 (43.53–57.63)

0.1042

8.30 (−1.11 to 17.70)

 Diabetic Women

35.97 (29.91–42.02)

38.56 (33.29–43.84)

50.23 (44.08–56.39)

49.31 (44.73–53.89)

50.83 (44.25–57.40)

<.0001

14.86 (5.91 to 23.80)

  1. aAll estimates are weighted to be representative of the US noninstitutionalized population. Means were age-standardized by the direct method to the 2000 US Census population using the age categories of 20–39, 40–59 years, and ≥60 years
  2. bApplying the Bonferroni method for adjusting for multiple comparisons for diabetic and non-diabetic men and women, there were 6 implied comparisons and an α = 0.008 (α = 0.05/6) was used