Table 3 Hazard Ratios for Alcohol-Attributable Disease Categories in 14,055,845 Women (French National Hospital Discharge database 2008–2012)
Alcohol-Attributable Disease Category | Total, n (%) | AUDs, n (%) | Mean (SD) age at incidence | Hazard Ratio with AUDs (95% CI) | |
|---|---|---|---|---|---|
AUDs | No AUDs | ||||
Liver diseases | |||||
Cirrhosis | 250,148 (1.78) | 52,348 (20.9) | 60.2 (12.5) | 65.6 (18.3) | 19.28 (10.09–19.47) |
Liver cancer | 21,171 (0.15) | 3690 (17.4) | 66.4 (11.2) | 71.7 (13.8) | 13.24 (12.76–13.73) |
Pancreatic diseases | |||||
Acute pancreatitis | 59,304 (0.42) | 6737 (11.4) | 50.4 (14.2) | 61.1 (20.9) | 8.56 (8.34–8.78) |
Chronic pancreatitis | 32,289 (0.23) | 6490 (20.1) | 54.0 (13.3) | 64.2 (17.8) | 15.36 (14.93–15.80) |
Pancreatic cancer | 38,627 (0.23) | 858 (2.2) | 63.6 (12.5) | 72.0 (13.2) | 1.44 (1.35–1.54) |
Upper aerodigestive tract cancers | |||||
Head and neck cancer | 24,814 (0.18) | 3255 (13.1) | 56.9 (9.0) | 65.3 (14.9) | 7.54 (7.26–7.83) |
Larynx cancer | 5267 (0.04) | 924 (17.5) | 57.6 (8.7) | 63.9 (13.0) | 9.68 (9.00–10.41) |
Esophageal cancer | 9399 (0.07) | 926 (9.9) | 61.0 (9.6) | 69.8 (13.2) | 6.23 (5.81–6.67) |
Colorectal cancer | 165,510 (1.18) | 2584 (1.6) | 67.3 (11.1) | 71.2 (13.7) | 1.09 (1.05–1.14) |
Breast cancer | 461,426 (3.28) | 6108 (1.3) | 62.3 (11.9) | 62.6 (14.4) | 0.65 (0.63–0.67) |
Cardiovascular diseases | |||||
Ischemic heart disease | 717,549 (5.10) | 12,170 (1.7) | 66.5 (13.1) | 76.1 (12.7) | 1.45 (1.43–1.48) |
Congestive heart failure | 829,405 (5.90) | 17,822 (2.2) | 68.4 (12.9) | 80.0 (11.6) | 2.35 (2.32–2.39) |
Atrial fibrillation | 818,585 (5.82) | 13,547 (1.7) | 71.9 (10.8) | 79.9 (10.4) | 1.84 (1.81–1.87) |
Ischemic stroke | 377,120 (2.68) | 8562 (2.3) | 65.9 (12.9) | 75.8 (14.2) | 1.92 (1.88–1.97) |
Hemorrhagic and other non-ischemic stroke | 100,700 (0.72) | 3864 (3.8) | 61.3 (13.1) | 72.0 (16.8) | 2.66 (2.58–2.75) |
Dementia | 675,778 (4.81) | 19,720 (2.9) | 69.4 (13.3) | 83.3 (8.1) | 4.27 (4.21–4.33) |
Infectious diseases | |||||
Pneumococcal pneumonia | 20,642 (0.15) | 1193 (5.8) | 55.5 (13.5) | 67.5 (20.0) | 4.35 (4.10–4.62) |
Tuberculosis | 36,103 (0.26) | 889 (2.5) | 59.8 (15.0) | 65.7 (20.8) | 1.80 (1.68–1.92) |
Injuries | |||||
Non-intentional injury | 404,365 (2.88) | 17,364 (4.3) | 61.5 (15.2) | 71.8 (20.5) | 4.49 (4.42–4.56) |
Self-harm | 223,769 (1.59) | 24,893 (11.1) | 45.2 (12.2) | 40.6 (18.0) | 8.90 (8.78–9.03) |
Other intentional injury | 17,958 (0.13) | 2619 (14.6) | 46.5 (13.3) | 46.5 (22.7) | 12.58 (12.05–13.13) |