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Table 3 Hazard Ratios for Alcohol-Attributable Disease Categories in 14,055,845 Women (French National Hospital Discharge database 2008–2012)

From: Alcohol use disorders and associated chronic disease – a national retrospective cohort study from France

Alcohol-Attributable Disease Category Total, n (%) AUDs, n (%) Mean (SD) age at incidence Hazard Ratio with AUDs (95% CI)
AUDs No AUDs
Liver diseases
 Cirrhosis 250,148 (1.78) 52,348 (20.9) 60.2 (12.5) 65.6 (18.3) 19.28 (10.09–19.47)
 Liver cancer 21,171 (0.15) 3690 (17.4) 66.4 (11.2) 71.7 (13.8) 13.24 (12.76–13.73)
Pancreatic diseases
 Acute pancreatitis 59,304 (0.42) 6737 (11.4) 50.4 (14.2) 61.1 (20.9) 8.56 (8.34–8.78)
 Chronic pancreatitis 32,289 (0.23) 6490 (20.1) 54.0 (13.3) 64.2 (17.8) 15.36 (14.93–15.80)
 Pancreatic cancer 38,627 (0.23) 858 (2.2) 63.6 (12.5) 72.0 (13.2) 1.44 (1.35–1.54)
Upper aerodigestive tract cancers
 Head and neck cancer 24,814 (0.18) 3255 (13.1) 56.9 (9.0) 65.3 (14.9) 7.54 (7.26–7.83)
 Larynx cancer 5267 (0.04) 924 (17.5) 57.6 (8.7) 63.9 (13.0) 9.68 (9.00–10.41)
 Esophageal cancer 9399 (0.07) 926 (9.9) 61.0 (9.6) 69.8 (13.2) 6.23 (5.81–6.67)
Colorectal cancer 165,510 (1.18) 2584 (1.6) 67.3 (11.1) 71.2 (13.7) 1.09 (1.05–1.14)
Breast cancer 461,426 (3.28) 6108 (1.3) 62.3 (11.9) 62.6 (14.4) 0.65 (0.63–0.67)
Cardiovascular diseases
 Ischemic heart disease 717,549 (5.10) 12,170 (1.7) 66.5 (13.1) 76.1 (12.7) 1.45 (1.43–1.48)
 Congestive heart failure 829,405 (5.90) 17,822 (2.2) 68.4 (12.9) 80.0 (11.6) 2.35 (2.32–2.39)
 Atrial fibrillation 818,585 (5.82) 13,547 (1.7) 71.9 (10.8) 79.9 (10.4) 1.84 (1.81–1.87)
 Ischemic stroke 377,120 (2.68) 8562 (2.3) 65.9 (12.9) 75.8 (14.2) 1.92 (1.88–1.97)
 Hemorrhagic and other non-ischemic stroke 100,700 (0.72) 3864 (3.8) 61.3 (13.1) 72.0 (16.8) 2.66 (2.58–2.75)
Dementia 675,778 (4.81) 19,720 (2.9) 69.4 (13.3) 83.3 (8.1) 4.27 (4.21–4.33)
Infectious diseases
 Pneumococcal pneumonia 20,642 (0.15) 1193 (5.8) 55.5 (13.5) 67.5 (20.0) 4.35 (4.10–4.62)
 Tuberculosis 36,103 (0.26) 889 (2.5) 59.8 (15.0) 65.7 (20.8) 1.80 (1.68–1.92)
Injuries
 Non-intentional injury 404,365 (2.88) 17,364 (4.3) 61.5 (15.2) 71.8 (20.5) 4.49 (4.42–4.56)
 Self-harm 223,769 (1.59) 24,893 (11.1) 45.2 (12.2) 40.6 (18.0) 8.90 (8.78–9.03)
 Other intentional injury 17,958 (0.13) 2619 (14.6) 46.5 (13.3) 46.5 (22.7) 12.58 (12.05–13.13)