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Table 3 Event rates and hazard ratios of first liver-related event according to various BMI and alcohol combinations

From: Risk of chronic liver disease in post-menopausal women due to body mass index, alcohol and their interaction: a prospective nested cohort study within the United Kingdom Collaborative Trial of Ovarian Cancer Screening (UKCTOCS)

BMI category (kg/m2)

Alcohol category (units/week)

None

<1–15

16–20

≥21

 

First event rate per 1000 person years (95% confidence intervals)

<25

0.52 (0.3–0.8)

0.42 (0.3–0.5)

0.50 (0.1–1.3)

1.00 (0.3–2.6)

25 - <30

0.83 (0.6–1.2)

0.57 (0.4–0.7)

0.84 (0.3–2.0)

1.81 (0.6–4.2)

≥30

1.43 (1.0–1.9)

0.88 (0.7–1.1)

0.98 (0.1–3.5)

1.68 (0.2–6.1)

 

Hazard ratio (95% confidence intervals) adjusted for smoking, hypertension, heart disease, hypercholesterolaemia, diabetes and IMD

<25

1 (reference)

0.91 (0.56–1.47)

1.03 (0.35–2.99)

1.93 (0.66–5.62)

25 - <30

1.46 (0.85–2.50)

1.34 (0.71–1.83)

1.61 (0.61–4.26)

3.32 (1.25–8.81)

≥30

2.28 (1.35–3.86)

1.58 (0.96–2.61)

1.67 (0.39–7.15)

2.86 (0.67–12.21)

 

Hazard ratio (95% confidence intervals) adjusted for hypertension, heart disease, hypercholesterolemia and diabetes

<25

1 (reference)

0.85 (0.53–1.37)

1.07 (0.37–3.09)

2.13 (0.74–6.17)

25 - <30

1.51 (0.89–2.55)

1.11 (0.69–1.76)

1.74 (0.66–4.57)

3.69 (1.40–9.72)

≥30

2.35 (1.40–3.95)

1.59 (0.97–2.60)

1.89 (0.44–8.01)

3.16 (0.74–13.41)