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Table 1 Baseline characteristics, number of first events according to BMI category and in all participants, and hazard ratios for LRE for potential confounders (continuousa and categoricalb variables)

From: Risk of chronic liver disease in post-menopausal women due to body mass index, alcohol and their interaction: a prospective nested cohort study within the United Kingdom Collaborative Trial of Ovarian Cancer Screening (UKCTOCS)

Characteristic BMI category (kg/m2) All participants Hazard ratio (95% confidence intervals)
<25 25 - < 30 ≥30
Total, n (%) 42,452 (44.6) 35,073 (36.9) 17,601 (18.5) 95,126  
Recruitment age, median (years) 60.0 (50–74) 61.0 (50–74) 60.0 (50–74) 60.0 (50–74) 1.01a (0.99–1.02)
Smoker, n (%) 14,740 (34.7) 12,616 (36.0) 6621 (37.6) 33,977 (35.7) 1.89b (1.52–2.35)
Hypertension, n (%) 9477 (22.3) 12,116 (34.5) 8440 (48.0) 30,033 (31.6) 1.38b (1.11–1.73)
Heart disease, n (%) 1721 (4.1) 2086 (5.9) 1416 (8.0) 5223 (5.5) 2.17b (1.53–3.06)
Hypercholesterolemia, n (%) 8001 (18.8) 9148 (26.1) 5440 (30.9) 22,589 (23.7) 1.68b (1.33–2.11)
Diabetes, n (%) 836 (2.0) 1689 (2.6) 2263 (12.9) 4788 (5.0) 2.76b (1.99–3.83)
IMD, mean 17.0 18.7 21.3 18.5 1.09a (1.01–1.03)
Alcohol consumption (units/week)
 None 8479 (20.0) 8189 (23.3) 5547 (31.5) 22,215 (23.4) 1b (reference)
  < 1–15 31,811 (74.9) 25,324 (72.2) 11,473 (65.2) 68,608 (72.1) 0.64b (0.51–0.82)
 16–20 1448 (3.4) 1067 (3.0) 366 (2.1) 2881 (3.0) 0.82b (0.44–1.53)
  ≥ 21 714 (1.7) 493 (1.4) 215 (1.2) 1422 (1.5) 1.66b (0.89–3.09)
Alcohol consumption (units/week) Number of first LREs  
 None 23 36 42 101  
  < 1–15 71 77 55 202  
 16–20 17 10 3 11  
  ≥ 21 4 5 2 11  
 Total 102 123 100 325  
  1. BMI body mass index, IMD Index of Multiple Deprivation, LRE liver-related event