Skip to main content

Table 1 Reported RDT sensitivity and specificity data for included studies

From: Use of malaria RDTs in various health contexts across sub-Saharan Africa: a systematic review

Author Year Sensitivity (95% CI) Specificity (95% CI)
Formal Health Care Sector
 Ashton 2010 85.6% 92.4–92.7%
 Baiden 2012 100% 73.0% (67–78)
 Chinkhumba 2010 90–97% 39–68%
 de Oliveira 2009 91.7 (80.8–100.0) 96.7 (92.8–100.0)
 Diarra 2012 89.6% (88.1–90.9) 81.1% (78.8–83.2)
 Gerstla 2010 99.4% (96.8–100.0) 96.0% (91.9–98.4)
 Gerstlb 2010 98.8% (95.8–99.8) 74.7% (67.6–81.0)
 Guthmann 2002 97% 88%
 Hopkinsa 2007 85% 99.8%
 Hopkinsb 2007 92% 93%
 McMorrow 2008 64.8% 87.8%
 McMorrow 2010 90.7% 73.5%
 Moonasar 2009 85% 96%
 Morankar 2011 93% 99.4%
 Msellem 2009 94% 88%
 Mtove 2011 97.5% (96.9–98.0) 65.3% (63.8–66.9)
 Nicastrip 2009 69.2% 100%
 Osei-Kwakye 2013 97.7% (95.8–99.0) 58.1% (53.8–62.3)
 Ouattara 2011 97.2% 95.4%
 Shakely 2013 78.6% (70.8–85.1) 99.7% (99.5–99.9)
 Shakelyp 2013 76.5% (69.0–83.9) 99.9% (99.7–100)
 Shekalaghe 2013 94.7% (89.8–97.3) 95.6% (94.2–96.6)
Retail Sector
 Ansah 2015 98–100% 30–98%
 Mbonye 2015 91.7% 63.1%
Community Health Workers
 Ishengomac 2011 88.6% 88.2%
 Ishengomad 2011 63.4% 94.3%
 Mubi 2011 85.3% 59.8%
 Ndyomugyenyie 2016 72.1% 83.3%
 Ndyomugyenyif 2016 20.8% 98.1%
 Ratsimbasoae 2012 90.2% (81.7–95.7) 87.2% (78.3–93.4)
 Ratsimbasoaf 2012 93.7% (69.8–99.4) 83.3% (35.9–99.6)
 Tiono 2013 97.9% (96.3–98.8) 53.4% (49.1–57.7)
 Willcox 2009 82.9% (78.0–87.1) 78.9% (63.9–89.7)
  1. Most studies used microscopy as a gold standard, those that used PCR are denoted with a p. Two studies [15, 56] used two different types of RDTs and calculated separate sensitivities and specificities for each; RDT sensitivity and specificity using a pLDH RDT is denoted with an a; RDT sensitivity and specificity using a HRP-2 RDT is denoted with a b. Another study [16] included sensitivity and specificity data from a cross-sectional study nested in a larger longitudinal study; RDT sensitivities and specificities from the longitudinal study are denoted with an c; RDT sensitivities and specificities from the cross-sectional study are denoted with a d. Two studies [59, 82] included sensitivity and specificity data from different transmission seasons; RDT sensitivities and specificities from higher-transmission seasons are denoted with an e; RDT sensitivities and specificities from lower-transmission seasons are denoted with a f. Ansah et al. reported sensitivities and specificities of individual drug shops, but not an overall value for either measure [70]. As such, a range of sensitivities and specificities is reported. Confidence intervals were included if reported in the original study