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Table 3 Changes over time in risk behaviour, symptoms of sexually transmitted infection and HIV incidence, by group

From: Using surrogate vaccines to assess feasibility and acceptability of future HIV vaccine trials in men: a randomised trial in inner-city Johannesburg, South Africa

Behaviour

Group

Baseline (n = 150)

Month 3 (n = 143)

Month 6 (n = 139)

Month 9 (n = 134)

Month 12 (n = 135)

P #

Median sexual partners in past 3 months

IV

1 (1–2)

1 (1–2)

1 (1–2)

1 (1–2)

1 (1–2)

0.993

DV

1 (1–2)

1 (1–2)

1 (1–2)

1 (1–2)

1 (1–2)

P*

0.769

0.644

0.685

0.959

0.558

Median sexual acts in past 3 months

IV

9 (3–21)

6 (2–12)

5.5 (2–12)

5 (2–10)

6 (3–15)

-

DV

9 (3–20)

6 (3–14)

6 (3–11)

6 (3–11)

6 (3–12)

P*

0.795

0.339

0.392

0.489

0.972

Condom use in past 3 months

IV

55 (73.3%)

56 (81.1%)

55 (80.9%)

50 (79.4%)

52 (81.3%)

0.461

DV

62 (82.7%)

60 (87.0%)

57 (85.1%)

58 (86.6%)

55 (84.6%)

P*

0.168

0.352

0.517

0.274

0.611

HIV-positive sex-partnera, c

IV

2 (2.7%)

0 (0.0%)

0 (0.0%)

0 (0%)

0 (0.0%)

0.061

DV

3 (4.0%)

1 (1.3%)

2 (2.7%)

1 (1.3%)

2 (2.7%)

P*

0.500

0.500

0.248

0.500

0.248

Sexual acts while intoxicated in past 3 months

IV

12 (16.0%)

16 (21.3%)

13 (17.3%)

17 (22.7%)

18 (24.0%)

0.233

DV

18 (24.0%)

19 (25.3%)

18 (24.0%)

20 (26.7%)

19 (25.3%)

P*

0.221

0.562

0.313

0.570

0.850

Incident HIV infectionb, c

IV

-

0 (0.0%)

0 (0.0%)

0 (0.0%)

0 (0.0%)

0.299

DV

-

2 (2.7%)

1 (1.4%)

0 (0.0%)

0 (0.0%)

P*

-

0.245

0.497

-

-

  1. aWhere participant knows partner’s HIV status; *P value compares groups at every month; # P value across visits overall; b2 incident HIV infections at Month 2 in IV group; cFisher’s exact test