Components | Mild HFMD cases | Severe HFMD cases | ratio/differencea | p-value* |
---|---|---|---|---|
Long-term linear trend | ||||
 Biennial increase (%) | 124.46 (122.80, 126.14) | 91.20 (89.69, 92.74) | 1.36 (1.34,1.39) | <0.001 |
Semi-annual cycle | ||||
 peak value | 1.04 (1.00,1.07) | 0.87 (0.82,0.93) | 1.19 (1.11,1.27) | <0.001 |
 peak time (days) | 134.7 (133.77,135.68) | 131.48 (129.83,133.13) | 3.21 (1.42,5.08) | <0.001 |
Eight-monthly cycle | ||||
 peak value | 0.24 (0.20,0.27) | 0.21 (0.16,0.26) | 1.14 (0.88,1.52) | 0.081 |
 peak time (days) | 97.47 (91.34,103.51) | 74.78 (64.86,83.81) | 22.69 (11.03,34.24) | 0.001 |
Annual cycle | ||||
 peak value | 1.78 (1.73,1.83) | 3.08 (2.97,3.19) | 0.58 (0.55,0.60) | <0.001 |
 peak time (days) | 183.08 (181.79,184,48) | 176.52 (175.27,177.77) | 6.56 (4.89,8.52) | <0.001 |
Biennial cycle | ||||
 peak value | 0.40 (0.36,0.43) | 0.80 (0.75,0.86) | 0.49 (0.44,0.56) | <0.001 |
 peak time (days) | 466.49 (456.14,477.35) | 492.55 (483.99,502.11) | −26.06 (−40.96,−11.92) | <0.001 |
First year cycle of the overall periodic curve | ||||
 Start time (days) | 36 (35,38) | 27 (25,29) | 9 (7,11) | <0.001 |
 Major peak time (days) | 155 (153,156) | 156 (155,158) | −1 (−3,0) | 0.012 |
 Major peak value | 1.23 (1.19,1.28) | 2.10 (2.00,2.19) | 0.59 (0.56,0.62) | <0.001 |
 Minor peak time (days) | 288 (284,292) | - | - | - |
 Minor peak value | 0.44 (0.42,0.47) | - | - | - |
Second year cycle of the overall periodic curve | ||||
 Start time (days) | 391 (390,392) | 377 (375,379) | 14 (11,16) | <0.001 |
 Major peak time (days) | 510 (509,511) | 513 (512,514) | −3 (−4,−1) | <0.001 |
 Major peak value | 1.90 (1.85,1.96) | 4.20 (4.07,4.34) | 0.45 (0.43,0.47) | <0.001 |
 Minor peak time (days) | 661 (659,664) | - | - | - |
 Minor peak value | 0.42 (0.36,0.44) | - | - | - |