Act local, think global: how the Malawi experience of scaling up antiretroviral treatment has informed global policy

Table 4 Evolution of national and international guidance, and supporting evidence

Policy	Year of implementation in Malawi	Year recommended by WHO	Supporting evidence from randomized trials or systematic reviews
Lifelong cotrimoxazole preventive therapy	2006	2006 WHO Cotrimoxazole Guidelines [28]	Reference [51]
Task shifting for the delivery of ART	2003	2008 WHO Guidelines for task shifting [33]	References [32, 52]
Decentralization of ART delivery	2003	2013 WHO Consolidated Guidelines [47]	References [53, 54]
PMTCT Option B+	2011	2012 WHO Programmatic Update [46]	None
PMTCT Option B+	2011	2013 WHO Consolidated Guidelines [47]	None

ART antiretroviral therapy, PMTCT prevention of mother to child transmission of HIV

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