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Table 2 Proportion and odds of having the metabolic syndrome according to mother’s pre-pregnancy BMI and childhood adversity

From: The early life nutritional environment and early life stress as potential pathways towards the metabolic syndrome in mid-life? A lifecourse analysis using the 1958 British Birth cohort

  Metabolic syndrome    
  Men (N = 3395)
  N (%) p value OR (95 %CI) p value
Mother’s pre-pregnancy BMI
 Normal 883 (35.7) 0.001 1  
 Underweight 49 (38) 1.10 (0.77–1.59) 0.596
 Overweight 274 (42.3) 1.32 (1.11–1.57) 0.002
 Obese 68 (47.2) 1.61 (1.15–2.26) 0.006
Adverse childhood experiences
 None 922 (37.1) 0.06 1  
 One 253 (36.5) 0.97 (0.82–1.16) 0.76
 Two or more 99 (45.0) 1.38 (1.05–1.83) 0.02
  Women (N = 3347)
N (%) p value OR (95 %CI) p value
Mother’s pre-pregnancy BMI
 Normal 428 (17.9) <0.001 1  
 Underweight 32 (19.2) 1.09 (1.73–1.62) 0.673
 Overweight 164 (25.0) 1.53 (1.25–1.88) <0.001
 Obese 38 (29.7) 1.94 (1.31–2.88) <0.001
Adverse childhood experiences
 None 463 (18.7) 0.04 1  
 One 151 (22.8) 1.28 (1.04–1.58) 0.02
 Two or more 48 (22.4) 1.25 (0.90–1.76) 0.19