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Table 8 Regression analyses of the Day −1 to Day 5 % change in the amount of urine biomarker amount excreted against the % change in CPD

From: Reductions in biomarkers of exposure, impacts on smoking urge and assessment of product use and tolerability in adult smokers following partial or complete substitution of cigarettes with electronic cigarettes

Urine Biomarker Slope R-square P-Value
NNAL 0.4154 0.1518 0.0108
3-HPMA 0.6940 0.4105 <.0001
HMPMA 0.7878 0.4289 <.0001
CEMA 0.7096 0.4891 <.0001
1-OHP 0.6297 0.4227 <.0001
NNN 0.7766 0.3181 0.0001
MHBMA 0.7469 0.2874 0.0003
S-PMA 0.7259 0.4636 <.0001
Nicotine Equivalents −0.0296 0.0002 0.9316