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Table 3 Summary of the number of cigarettes smoked and estimated amount of nicotine delivered

From: Reductions in biomarkers of exposure, impacts on smoking urge and assessment of product use and tolerability in adult smokers following partial or complete substitution of cigarettes with electronic cigarettes

   Exclusive e-Cigarette use Dual use Nicotine cessation
  Tobacco rechargeable Cherry rechargeable Cherry disposable Tobacco rechargeable Cherry rechargeable Cherry disposable -
Screening Cigarettes 18.4 ± 7.1 17.3 ± 6.2 15.4 ± 3.3 18.7 ± 6.6 20.5 ± 7.3 21.1 ± 5.8 20.4 ± 7.5
   Day −1 Cigarettes 16.9 ± 5.1 15.8 ± 5.4 14.9 ± 1.5 14.5 ± 4.5 14.2 ± 2.0 14.8 ± 2.4 17.5 ± 4.9
   Day 1 Cigarettes NA NA NA 8.9 ± 3.1 9.6 ± 2.7 9.8 ± 2.0 NA
  E-cigarette nicotine 14.9 ± 15.2 17.7 ± 16.9 13.6 ± 11.0 8.9 ± 6.9 4.6 ± 3.3 5.6 ± 3.4 NA
   Day 2 Cigarettes NA NA NA 8.9 ± 2.9 9.5 ± 2.8 9.9 ± 1.9 NA
  E-cigarette nicotine 17.2 ± 15.1 17.6 ± 14.3 19.6 ± 16.8 11.1 ± 7.8 6.5 ± 5.5 7.4 ± 7.2 NA
   Day 3 Cigarettes NA NA NA 8.9 ± 3.0 9.5 ± 2.5 10.1 ± 2.0 NA
  E-cigarette nicotine 16.3 ± 13.4 19.8 ± 16.9 19.4 ± 20.0 12.4 ± 9.5 6.2 ± 6.5 9.4 ± 9.8 NA
   Day 4 Cigarettes NA NA NA 9.0 ± 3.2 9.7 ± 2.9 10.0 ± 2.0 NA
  E-cigarette nicotine 18.4 ± 14.6 20.8 ± 14.2 23.4 ± 21.0 13.3 ± 10.7 7.5 ± 8.3 9.9 ± 9.1 NA
   Day 5 Cigarettes NA NA NA 9.0 ± 3.3 9.6 ± 2.8 10.4 ± 2.2 NA
  E-cigarette nicotine 19.4 ± 16.6 22.9 ± 16.6 22.9 ± 20.5 12.7 ± 11.6 7.0 ± 9.3 9.1 ± 8.6 NA
   Day 1 through Day 5 Mean Cigarettes NA NA NA 44.7 ± 15.4 47.9 ± 13.6 50.5 ± 9.5 NA
E-cigarette nicotine 86.1 ± 70.5 98.9 ± 75.1 99.0 ± 86.8 61.8 ± 45.9 31.9 ± 30.1 38.9 ± 36.4 NA
  1. Values are presented as mean ± SD mg nicotine or cigarettes smoked
  2. Cessation group subjects reported smoking 20.4 ± 7.5 CPD during screening and smoked 17.5 ± 4.9 cigarettes on Day −1
  3. NA Not available