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Table 11 Day 5 evening and day 5 evening change from morning smoking urge statistical comparisons between use groups

From: Reductions in biomarkers of exposure, impacts on smoking urge and assessment of product use and tolerability in adult smokers following partial or complete substitution of cigarettes with electronic cigarettes

Comparison Day 5 evening comparisons Day 5 evening change from morning comparisons
First LSM (%) Second LSM (%) Difference (%) p-Value First LSM (%) Second LSM (%) Difference (%) p-Value
A1 vs C 63.00 66.32 −3.32 0.7589 −8.92 2.69 −11.61 0.2273
A2 vs C 43.32 66.32 −23.00 0.0355 −10.05 2.69 −12.75 0.1818
A3 vs C 49.91 66.32 −16.41 0.1323 −16.90 2.69 −19.59 0.0427
B1 vs C 45.74 66.32 −20.58 0.0611 −16.84 2.69 −19.53 0.0443
B2 vs C 37.69 66.32 −28.63 0.0094 −29.06 2.69 −31.75 0.0012
B3 vs C 40.90 66.32 −25.42 0.0229 −28.97 2.69 −31.66 0.0014
A1 vs B1 63.00 45.74 17.26 0.1111 −8.92 −16.84 7.92 0.4066
A2 vs B2 43.32 37.69 5.63 0.5971 −10.05 −29.06 19.00 0.0401
A3 vs B3 49.91 40.90 9.01 0.4108 −16.90 −28.97 12.07 0.2015
A1 vs A2 63.00 43.32 19.68 0.0668 −8.92 −10.05 1.14 0.9016
A1 vs A3 63.00 49.91 13.09 0.2226 −8.92 −16.90 7.98 0.3982
A2 vs A3 43.32 49.91 −6.58 0.5364 −10.05 −16.90 6.84 0.4594
B1 vs B2 45.74 37.69 8.05 0.4562 −16.84 −29.06 12.22 0.1921
B1 vs B3 45.74 40.90 4.84 0.6608 −16.84 −28.97 12.13 0.2019
B2 vs B3 37.69 40.90 −3.21 0.7664 −29.06 −28.97 −0.09 0.9921
  1. LSM Least-square means
  2. Use Groups
  3. A1: Exclusive Tobacco flavor rechargeable e-cigarette
  4. A2: Exclusive Cherry flavor rechargeable e-cigarette
  5. A3: Exclusive Cherry flavor disposable e-cigarette
  6. B1: Dual Classic Tobacco flavor rechargeable e-cigarette and a usual brand combustible cigarette
  7. B2: Dual Cherry flavor rechargeable e-cigarette and a usual brand combustible cigarette
  8. B3: Dual Cherry flavor disposable e-cigarette and a usual brand combustible cigarette
  9. C: Nicotine cessation
  10. p-values indicate statistically significant