Skip to main content

Table 1 Basic characteristics of the study population in relation to asthma at any time among offspring

From: Parental smoking and cessation during pregnancy and the risk of childhood asthma

 

Asthma*

No asthma*

p-value**

 

n = 2641 (6.7 %)

n = 36 665 (93.3 %)

 

Primipara

1 039 (39.3)

15 131 (41.3)

0.114

Maternal

   

Asthma

116 (4.4)

876 (2.4)

<0.001

GDMa

143 (5.4)

2 314 (6.3)

0.066

Hypertension

76 (2.9)

725 (2.0)

0.002

Preeclampsia

115 (4.4)

1 438 (3.9)

0.217

ARTb

183 (6.9)

1736 (4.7)

<0.001

Maternal age, years

28.7 (5.3)

29 (5.5)

0.313

<25

780 (29.5)

9 944 (27.1)

 

26-35

1 581 (59.9)

22 049 (60.1)

 

>35

280 (10.6)

4672 (12.7)

0.001

Mean prepregnancy BMIc, kg/m2

23.4 (4.5)

23.2 (4.3)

0.020

Mean number of previous pregnancies

1.5 (1.6)

1.4 (1.6)

0.08

Mean number of previous deliveries

1.1 (1.2)

1.0 (1.3)

0.57

Marital status

   

not married

900 (34.1)

13 238 (36.1)

 

married

1 741 (65.9)

23 427 (63.9)

0.036

Mode of delivery

   

Vaginal

2 040 (77.2)

29 925 (81.6)

 

Cesarean section

601 (22.8)

6 740 (18.4)

<0.001

Single

2 500 (94.7)

35 340 (96.4)

 

Twins

133 (5.0)

1 258 (3.4)

 

Triplets

8 (0.3)

67 (0.2)

<0.001

Premature delivery

380 (14.4)

2 594 (7.1)

<0.001

Boy

1 602 (60.7)

18 241 (50.2)

<0.001

Mean gestational age, w

38.4 (3.2)

39.2 (2.1)

<0.001

Apgar score 5 min <7

70 (2.7)

663 (1.8)

0.002

Chorioamnionitisd

48 (1.8)

414 (1.1)

0.002

Mean follow-up time of children, years*

4.2 (3.6)

9.3 (5.3)

<0.001

  1. *Values are mean (±2 SD) or N (%)
  2. ** p-value obtained in univariate model
  3. aGestational diabetes mellitus
  4. bART (assisted reprodution technology), including IVF (in-vitro fertilization), ICSI (intracytoplasmic sperm injection), insemination and ovulation induction by clomiphene and other medicines
  5. cData missing in 1984 (4.5 %) cases
  6. dData missing in 7 (0 %) cases