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Table 3 Effect estimates of adherence to statin therapy on cardiovascular mortality by calendar period

From: The effect of adherence to statin therapy on cardiovascular mortality: quantification of unmeasured bias using falsification end-points

Calendar years Small model Large model Difference in HR # events
HR 95 % CI HR 95 % CI
1994–2002 0.85 0.55 to 1.34 0.79 0.44 to 1.40 0.06 158
2003–2006 0.58 0.45 to 0.76 0.46 0.35 to 0.59 0.12 642
2007–2012 0.77 0.65 to 0.92 0.54 0.45 to 0.65 0.23 765
Overall (1994–2002) 0.70 0.61 to 0.81 0.53 0.46 to 0.61 0.17 1565
Falsification outcome (1994–2002) 0.93 0.97 to 1.09 0.68 0.58 to 0.80 0.25 1179