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Table 1 Criteria, case–control distribution and association between MetS and PCa, according to different MetS definitions

From: Metabolic syndrome and prostate cancer risk in a population-based case–control study in Montreal, Canada

MetS Definition

Criteria used in the study

Cases (N = 1937)

Controls (N = 1995)

ORa

CI 95 %

N

%

n

%

NCEP-ATPIII

At least 3 of these conditions:

476

24.9

629

31.8

0.70

0.60-0.82

- Dyslipidemia (counting for 2 conditions: low HDL-C and high TG)

- Type 2 diabetes

- Hypertension

- WC > 102 cm (or BMI > 30)

NCEP-ATPIII ico

NCEP-ATPIII criteria with waist-to-height ratio > 0.5 instead of WC > 102 cm

579

30.3

734

37.2

0.71

0.61-0.82

WHO

Type 2 diabetes + 2 other conditions among them:

149

7.8

279

14.1

0.54

0.44-0.68

- Hypertension

- BMI > 30 or waist-to-hip ratio > 0.9

- Dyslipidemia (as a simple condition)

IDF

- WC > 90 cm for Asiatic men and > 94 cm for others (or BMI > 30) + 2 other conditions among them:

427

22.3

527

26.6

0.75

0.64-0.88

- Type 2 diabetes

- Hypertension

- Dyslipidemia (counting for 2 conditions: low HDL-C and high TG)

  1. aAdjusted for age, family history of prostate cancer, ancestry, prostate cancer screening and family income.BMI, Body mass index; CI, Confidence interval; HDL-C, High-density lipoprotein cholesterol; IDF, International Diabetes Federation; NCEP-ATPIII, Adult Treatment Panel III from the National Cholesterol Education Program; OR, Odds ratio; TG: Triglycerides; WC, Waist circumference; WHO: World Health Organization