Characteristics real case | N | Bivariate analysis Hazard ratio7 (95 % CI) | Multivariate analysis Hazard ratio (95 % CI) |
---|---|---|---|
Sex | |||
Female | 429 | 1 | 1 |
Male | 301 | 1.69 (1.69, 2.12) | 1.22 (0.70, 2.10) |
Spouse treatment status | |||
Enrolled ART | 179 | 1 | 1 |
Not Enrolled ART | 254 | 2.54 (1.26, 5.13) | 1.31 (0.29, 5.98) |
Unknown | 212 | 2.88 (1.41, 5.85) | 1.32 (0.61, 2.86) |
Smoke Tobacco | |||
No | 636 | 1 | 1 |
Yes | 94 | 1.70 (1.00, 2.87) | 0.40 (0.12, 1.36) |
Use other substances | |||
No | 631 | 1 | 1 |
Yes | 98 | 1.87 (1.13, 3.09) | 1.12 (0.66, 1.54) |
Attending HIV related education | |||
No | 372 | 1 | 1 |
Yes | 358 | 0.68 (0.44, 1.05) | 0.87 (0.66, 1.90) |
Understanding HIV prophylaxis | |||
Poor | 374 | 1 | 1 |
Good | 356 | 0.70(0.46, 1.06) | 0.65 (0.45, 1.89) |
Understanding of Adherence to HIV medication | |||
Poor | 419 | 1 | 1 |
Good | 311 | 0.68 (0.44, 1.05) | 0.68 (0.38, 1.44) |
OIs before initiation of ART | |||
No OIs | 249 | 1 | |
Only one OIs | 280 | 1.27 (0.78, 2.07) | NA |
≥2 OIs | 201 | 0.73 (0.44, 1.23) | NA |
TB status before initiation of ART | |||
Absent | 711 | 1 | |
Present | 19 | 3.33 (1.54, 7.20) | 1.25 (0.68, 1.54) |
OIs after initiation of ART | |||
No OIs | 534 | 1 | 1 |
Only one OIs | 170 | 2.38 (1.51, 3.75) | 1.24 (1.06, 1.89) |
≥2OIs | 26 | 10.90 (6.13, 19.37) | 3.35 (1.46,7.69) |
TB after initiation of ART | |||
Absent | 662 | 1 | 1 |
Present | 68 | 1.82 (1.03, 3.22) | 1.428 (1.28, 3.39) |
Past prophylaxis | |||
Not Received | 269 | 1 | |
Received | 461 | 0.88 (0.59, 1.33) | NA |
Functional status | |||
Working | 495 | 1 | 1 |
Ambulatory | 194 | 2.81 (1.79, 4.41) | 1.79 (1.05, 3.07) |
Bedridden | 39 | 6.32 (3.42, 11.700) | 3.40 (1.61, 7.21) |
WHO clinical stage | |||
Stage I | 101 | 1 | 1 |
Stage II | 148 | 2.32 (0.64, 8.41) | NA |
Stage III | 413 | 5.06 (1.59, 16.13) | 2.01 (1.02, 4.35) |
Stage IV | 62 | 8.58 (2.46, 19.87) | 2.42 (1.19, 5.86) |
Hemoglobin by g/dl | |||
<10 | 110 | 1 | 1 |
≥10 | 620 | 0.17 (0.11, 0.26) | 0.22 (0.14, 0.37) |
CD4 counts at baseline | |||
<51 cells/mm3 | 106 | 1 | 1 |
51 –200 cells/mm3 | 398 | 0.23 (0.15, 0.35) | 0.26 (0.15, 0.45) |
201 –350 cell/mm3 | 195 | 0.13 (0.07, 0.25) | 0.20 (0.09, 0.43) |
>350 cell/mm3 | 31 | 0.06 (0.01, 0.46) | 0.12 (0.02, 0.91) |
Weight at baseline | |||
≤45 | 160 | 1 | 1 |
46 –55 | 329 | 0.58 (0.37, 0.93) | 0.52 (0.29, 1.93) |
56 – 65 | 184 | 0.39 (0.21, 0.70) | 0.51 (0.28, 1.18) |
>65 | 57 | 0.24 (0.07, 0.75) | 0.55 (0.16, 1.19) |
Regimen at baseline | |||
1a = d4t-3TC-NVP | 268 | 1 | 1 |
1b = d4t-3TC-EFV | 67 | 0.71 (0.32, 1.58) | NA |
1c = AZT-3TC-NVP | 197 | 0.55 (0.31, 0.97) | 1.63 (0.87, 3.05) |
1d = AZT-3TC-EFV | 51 | 0.84 (0.36, 1.98) | NA |
TDF-3TC_NVP | 141 | 1.39 (0.82, 2.35) | NA |
Regimen Adherence | |||
Good | 675 | 1 | 1 |
Fair | 18 | 4.36 (2.00, 9.50) | 1.66 (0.59, 4.62) |
Poor | 37 | 5.94 (3.49, 10.14) | 2.70 (1.40, 5.20) |