Table 2 Summary of the relative risks (ratios) of major cardiovascular outcomes and total mortality

Coronary disease

Low

0.67 (0.47–0.97)*

0.70 (0.51–0.97)*

1.01 (0.84–1.21)

Moderate

0.68 (0.50–0.93)*

0.70 (0.52–0.94)*

0.96 (0.75–1.23)

Heavy

0.69 (0.49–0.96)*

0.66 (0.44–0.99)*

0.90 (0.66–1.22)

Total mortality

Low

0.74 (0.60–0.92)*

0.87 (0.71–1.07)

1.07 (0.98–1.17)

Moderate

0.80 (0.68–0.95)*

0.95 (0.83–1.08)

1.10 (1.00–1.21)*

Heavy

1.00 (0.81–1.22)

1.20 (0.99–1.46)

1.09 (0.99–1.21)

Cardiac death

Low

0.93 (0.85–1.01)

0.84 (0.71–0.99)*

0.93 (0.83–1.04)

Moderate

0.85 (0.78–0.92)*

0.86 (0.68–1.08)

0.99 (0.87–1.14)

Heavy

0.93 (0.70–1.23)

1.04 (0.74–1.46)

1.14 (0.99–1.32)

Stroke

Low

0.89 (0.79–1.00)

0.89 (0.76–1.06)

0.99 (0.83–1.16)

Moderate

0.91 (0.81–1.02)

0.79 (0.69–0.91)*

0.90 (0.74–1.10)

Heavy

1.19 (0.93–1.52)

1.37 (0.92–2.04)

1.35 (0.77–2.35)

Ischemic stroke

Low

0.83 (0.69–0.99)*

0.79 (0.68–0.92)*

0.94 (0.74–1.20)

Moderate

0.91 (0.77–1.08)

0.81 (0.67–0.96)*

0.88 (0.66–1.16)

Heavy

1.18 (0.96–1.44)

1.12 (0.86–1.45)

1.04 (0.80–1.36)