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Table 1 HPV genotype distribution in the different EDiTH studies

From: Potential impact of a nonavalent HPV vaccine on the occurrence of HPV-related diseases in France

  Invasive cervical cancers High-grade cervical neoplasias Low-grade squamous intraepithelial lesions External acuminata condylomata Anal cancer Oropharyngeal carcinomas
  n n n n n n
HPV (+) 501 (97.1) 484 (98.2) 390 (98.2) 418 (98.8) 354 (96.7) 146 (46.5)
HPV (-) 15 (2.9) 9 (1.8) 7 (1.8) 5 (1.2) 12 (3.3) 168 (53.5)
Total 516 (100) 493 (100) 397 (100) 423 (100) 366 (100) 314 (100)
Total single infections 386 (74.8) 333 (67.5) 192 (48.4) 281 (66.4) 265 (72.4) 138 (43.9)
Total single infections 6/11/16/18 316 (61.2) 203 (41.2) 50 (12.6) 248 (58.6) 234 (63.9) 130 (41.4)
  Single infections 6 1 (0.2) 0 (0.0) 11 (2.8) 195 (46.1) 13 (3.6) 0 (0.0)
  Single infections 11 1 (0.2) 1 (0.2) 0 (0.0) 42 (9.9) 4 (1.1) 0 (0.0)
  Single infections 16 275 (53.3) 199 (40.4) 31 (7.8) 11 (2.6) 216 (59.0) 130 (41.4)
  Single infections 18 39 (7.6) 3 (0.6) 8 (2.0) 0 (0.0) 1 (0.3) 0 (0.0)
Total single infections 31/33/45/52/58 46 (8.9) 96 (19.5) 34 (8.6) 3 (0.7) 23 (6.3) 0 (0.0)
  Single infections 31 17 (3.3) 41 (8.3) 8 (2.0) 1 (0.2) 4 (1.1) 0 (0.0)
  Single infections 33 11 (2.1) 27 (5.5) 1 (0.3) 0 (0.0) 11 (3.0) 0 (0.0)
  Single infections 45 9 (1.7) 0 (0.0) 6 (1.5) 0 (0.0) 0 (0.0) 0 (0.0)
  Single infections 52 6 (1.2) 13 (2.6) 8 (2.0) 1 (0.2) 5 (1.4) 0 (0.0)
  Single infections 58 3 (0.6) 15 (3.0) 11 (2.8) 1 (0.2) 3 (0.8) 0 (0.0)
Total single infections 6/11/16/18/31/33/45/52/58 362 (70.2) 299 (60.6) 84 (21.2) 251 (59.3) 257 (70.2) 130 (41.4)
  Single infections others 24 (4.7) 34 (6.9) 108 (27.2) 30 (7.1) 8 (2.2) 8 (2.5)
Total multiple infections 115 (22.3) 151 (30.6) 198 (49.9) 137 (32.4) 89 (24.3) 8 (2.5)
  Multiple infections 6/11/16/18 excluding any other HPV genotypes 41 (7.9) 11 (2.2) 4 (1.0) 19 (4.5) 24 (6.6) 0 (0.0)
  Multiple infections 6/11/16/18 with or without another HPV genotype 108 (20.9) 116 (23.5) 83 (20.9) 125 (29.6) 76 (20.8) 3 (1.0)
  Multiple infections 6/11/16/18/31/33/45/52/58 excluding any other HPV genotypes 74 (14.3) 79 (16.0) 19 (4.8) 39 (9.2) 39 (10.7) 0 (0.0)
  Multiple infections 6/11/16/18/31/33/45/52/58 with or without another HPV genotype 113 (21.9) 142 (28.8) 139 (35.0) 131 (31.0) 84 (23.0) 8 (2.5)
  Multiple infections other HPV excluding 6/11/16/18/31/33/45/52/58 2 (0.4) 9 (1.8) 59 (14.9) 6 (1.4) 5 (1.4) 0 (0.0)
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