Table 1 Major study design differences between Helping HAND 1 and Helping HAND 2
Characteristics | Helping HAND 1 | Helping HAND 2 | Goal of the Change |
|---|---|---|---|
Enrollment | Â | Â | Â |
Study sites | MGH | MGH, NSMC, UPMC | Increase generalizability |
Enrollment criteria | Exclude active alcoholics | Include active alcoholics | Increase generalizability |
Exclude past year substance users (except marijuana) | Substance use allowed unless current admission was for IV drug overdose | ||
No suicidal attempt in past year | No suicidal attempt in past 3Â months | ||
Patients with HIV infection | Not prioritized | Prioritized | Increase enrollment of vulnerable population with high prevalence of smoking |
Intervention | Â | Â | Â |
Counseling after hospital discharge | Hospital tobacco counselor by telephone | Quit Coach by telephone | Streamline access to live counselor by linking IVR call directly to counseling resource using ‘real world’ counseling resource |
Nicotine Replacement Therapy after discharge | Refilled and shipped by hospital study staff | NRT refilled through Quit Coach and shipped from Alere warehouse | Streamline medication refill process using ‘real-world’ design |
Follow-up | Â | Â | Â |
Follow-up calls | 1, 3, and 6Â months | 1, 3 and 6Â months (all) 12Â months if continuously abstinent at 6-month follow-up | Determine stability of cessation |