Table 3 Changes in projected TB related outcomes relative to baseline of no intervention, per 1,000 general population, in Indonesia over 20 years
From: Modeling the impact of tuberculosis interventions on epidemiologic outcomes and health system costs
Intervention | Specific parameter changed1 | Change in outcomes related to primary active cases and ranking of impact3 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Â | Parameter | Pre-intervention | Post-intervention | Death during diagnosis and treatment phase | Cure due to treatment | Secondary cases generated from primary cases | Health system costs | ||||
Change in outcome | Rank of impact | Change in outcome | Rank of impact | Change in outcome | Rank of impact | Change in outcome | Rank of impact | ||||
Baseline | - | - | - | 12 · 52 | - | 0 · 97 | - | 28 · 87 | - | $2,641 · 47 | - |
Community Education | Patient delay2 | 11% | 6% | −0 · 14 | 7 | 0 · 02 | 7 | −0 · 33 | 7 | 55 · 24 | 10 |
DOTS expansion for diagnosis | Incorrect Diagnostic Test (in public sector) | 60% | 35% | −0 · 62 | 2 | 0 · 27 | 4 | −1 · 49 | 2 | 661 · 09 | 14 |
Diagnostic Delay2 (in public sector) | 8% | 0 · 5% | −0 · 04 | 10 | 0 · 01 | 10 | −0 · 16 | 10 | 29 · 16 | 7 | |
Loss to follow up during Diagnosis (in public sector) | 25% | 14% | −0 · 15 | 6 | 0 · 07 | 6 | −0 · 36 | 6 | 159 · 37 | 12 | |
DOTS Expansion for Treatment | Incorrect Treatment (in public sector) | 79% | 13% | −0 · 50 | 4 | 1 · 36 | 2 | −0 · 98 | 4 | 5 · 15 | 5 |
Non specific NTP Strengthening | Access Government Facility | 43% | 73% | −0 · 10 | 8 | 0 · 02 | 7 | −0 · 25 | 8 | 123 · 40 | 11 |
Private Sector interventions | Incorrect Diagnostic test (in private sector) | 62% | 36% | −0 · 77 | 1 | 0 · 37 | 3 | −1 · 84 | 1 | 814 · 07 | 15 |
Diagnostic Delay2 (in private sector) | 11% | 0 · 7% | −0 · 07 | 9 | 0 · 02 | 7 | −0 · 24 | 9 | 44 · 02 | 8 | |
Loss to follow up during Diagnosis (private sector) | 25% | 14% | −0 · 17 | 5 | 0 · 08 | 5 | −0 · 41 | 5 | 181 · 69 | 13 | |
Incorrect Treatment (in private sector) | 77% | 13% | −0 · 56 | 3 | 1 · 51 | 1 | −1 · 08 | 3 | 5 · 72 | 6 | |
HIV/ ART therapy programmes | HIV/TB Death rate | 12% | 10% | 0 · 00 | 11 | 0 · 00 | 11 | 0 · 00 | 13 | 0 · 00 | 2 |
HIV/TB Relapse rate | 16% | 1% | 0 · 00 | 11 | 0 · 00 | 11 | 0 · 00 | 13 | 0 · 00 | 2 | |
HIV/TB Reactivation rate | 3 · 4% | 2% | 0 · 00 | 11 | 0 · 00 | 11 | −0 · 01 | 11 | −0 · 81 | 1 | |
MDR-TB related interventions | DST performed | 20% | 50% | 0 · 00 | 11 | 0 · 00 | 11 | −0 · 01 | 11 | 52 · 31 | 9 |
Loss to follow up during MDR Treatment | 22% | 11% | 0 · 00 | 11 | 0 · 00 | 11 | 0 · 00 | 13 | 1 · 07 | 4 | |