From: Nicotine dependence in an isolated population of Kashubians from North Poland: a population survey
SNP/Genotype | FTND No. of subjects | OR(95% CI)p-value | CPD* No. of subjects | OR (95% CI) p-value | HSI No. of subjects | OR (95% CI)p-value | TTF No. of subjects | OR (95% CI) p-value | ||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
<4 | ≥4 | ≤20 | >20 | <3 | ≥3 | ≤5 min | >5 min | |||||
rs16969968 at CHRNA5/ | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
GG | 218 | 252 | 1 | 397 | 44 | 1 | 251 | 219 | 1 | 103 | 367 | 1 |
AA + AG | 222 | 277 | 1.08 (0.83-1.40) 0.56 | 391 | 70 | 1.63 (1.09-2.45) 0.017** | 251 | 248 | 1.13 (0.88-1.46) 0.33 | 127 | 372 | 1.22 (0.91-1.65) 0.19 |
rs578776 at CHRNA3/ | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
CC | 232 | 269 | 1 | 403 | 62 | 1 | 264 | 237 | 1 | 119 | 382 | 1 |
TT + TC | 208 | 260 | 1.09 (0.84-1.41) 0.52 | 385 | 52 | 0.89 (0.60-1.30) 0.56 | 238 | 230 | 1.08 (0.84-1.39) 0.55 | 111 | 357 | 0.99 (0.73-1.33) 0.94 |
rs12914008 at CHRNB4/ | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
GG | 398 | 485 | 1 | 717 | 105 | 1 | 455 | 428 | 1 | 209 | 674 | 1 |
AA + AG | 42 | 44 | 0.86 (0.55-1.35) 0.52 | 71 | 9 | 0.87 (0.42-1.80) `0.70 | 47 | 39 | 0.88 (0.57-1.38) `0.58 | 21 | 65 | 1.04 (0.61-1.77) 0.90 |