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Table 4 Mediation effect of percentage body fat, body mass index and waist circumference on the association between total daily steps/aerobic time and clinical measures

From: The association between daily steps and health, and the mediating role of body composition: a pedometer-based, cross-sectional study in an employed South African population

Mediator

Independent variable

Outcome Variable

c path(SE)

a path(SE)

b path(SE)

c’path(SE)

ab path(95%CI)

% mediation

Percentage body fat

Total steps (steps/day)

       
  

SBP (mmHg)(n = 233)

-2.70 (0.94)

-3.61 (0.67)

0.33 (0.94)

-1.50(0.98)

-1.19 (-2.46;-0.53)

44

  

DBP(mmHg)(n = 233)

-2.75 (0.78)

-3.61 (0.67)

0.28 (0.08)

-1.76 (0.81)

-0.99 (-1.63;-0.49)

36

  

BC (mmol/L)(n = 195)

-0.18 (0.08)

-3.44 (0.74)

0.02 (0.01)

-0.11(0.08)

-0.07 (-0.16;-0.0006)

38

  

BG (mmol/L)(n = 189)

-0.31 (0.14)

-3.37 (0.74)

0.04 (0.01)

-0.19(0.15)

-0.13 (-0.35;-0.24)

42

 

Aerobic time (minutes/day)

       
  

SBP (mmHg)(n = 233)

-3.71 (1.37)

-4.39 (0.98)

0.34 (0.09)

-2.22(1.39)

-1.48 (-2.72;-0.70)

60

  

DBP (mmHg)(n = 233)

-4.34 (1.12v)

-4.39 (0.98)

0.27 (0.07)

-3.14 (1.14)

-1.19 (-1.98;-0.67)

27

  

BC (mmol/L)(n = 195)

-0.18(0.13)

-4.00 (1.17)

0.02 (0.01)

-0.09(0.13)

-0.08 (-0.19;-0.01)

44

  

BG (mmol/L)(n = 189)

-0.30(0.23)

-4.13 (1.20)

0.04 (0.01)

-0.13(0.23)

0.17 (-0.46;-0.04)

57

Body mass index

Total steps (steps/day)

       
  

SBP (mmHg)(n = 290)

-2.38 (0.84)

-1.04 (0.34)

0.60 (0.14)

-1.75(0.82)

-0.63 (-1.31;-0.20)

26

  

DBP(mmHg)(n = 290)

-2.61 (0.69)

-1.04(0.34)

0.51 (0.11)

-2.08 (0.68)

-0.53 (-0.95;-0.20)

20

  

BC (mmol/L)(n = 247)

-0.16 (0.07)

-0.71(0.38)

0.01(0.01)

-0.15 (0.07)

-0.009(-0.05;0.005)

06

  

BG (mmol/L)(n = 240)

-0.27 (0.12)

-0.77 (0.38)

0.07 (0.02)

-0.27 (0.12)

-0.05 (-0.17;-0.007)

19

 

Aerobic time (minutes/day)

       
  

SBP (mmHg)(n = 290)

-2.81 (1.17)

-0.67(0.50)

0.63 (0.14)

-2.38 (1.17)

-0.43(-1.18;0.10)

15

  

DBP (mmHg)(n = 290)

-3.40 (0.10)

-0.67(0.50)

0.54 (0.11)

-3.03 (0.96)

-0.36(-0.87;0.09)

11

  

BC (mmol/L)(n = 247)

-0.12(0.11)

-0.38(0.57)

0.02(0.01)

-0.12(0.11)

-0.01(-0.05;0.01)

08

  

BG (mmol/L)(n = 240)

-0.25(-0.18)

-0.37(0.60)

0.07 (0.02)

-0.22(0.18)

-0.03(-0.14;0.04)

12

Mediator

Independent variable

Outcome Variable

c path (SE)

a path (SE)

b path (SE)

c’ path (SE)

ab path (95% CI)

% mediation

Waist circumference

Total steps (steps/day)

       
  

SBP (mmHg)(n = 292)

-2.60 (0.83)

-3.91 (0.76)

0.34 (0.06)

-1.26(0.82)

-1.34 (-2.21;-0.76)

52

  

DBP(mmHg)(n = 292)

-2.90 (0.67)

-3.91 (0.76)

0.27 (0.05)

-1.83 (0.67)

-1.05 (-1.65;-0.60)

36

  

BC (mmol/L)(n = 243)

-0.15 (0.07)

-3.43 (0.83)

0.01(0.01)

-0.12(0.07)

-0.03(-0.09;0.001)

20

  

BG (mmol/L)(n = 236)

-0.30 (0.12)

-3.34 (0.84)

0.03 (0.01)

-0.20(0.12)

-0.10 (-0.19;-0.05)

33

 

Aerobic time (minutes/day)

       
  

SBP (mmHg)(n = 292)

-3.30 (1.21)

-3.24 (1.14)

0.35 (0.06)

-2.15(1.16)

-1.14 (-2.07;-0.46)

35

  

DBP (mmHg)(n = 292)

-3.91 (0.99)

-3.24 (1.14)

0.28 (0.05)

-2.99 (0.95)

-0.91 (-1.62;-0.36)

23

  

BC (mmol/L)(n = 243)

-0.12(0.11)

-3.01 (1.31)

0.01 (0.01)

-0.01(0.11)

-0.03 (-0.10;-0.0002)

25

  

BG (mmol/L)(n = 236)

-0.25(0.19)

-3.31 (1.33)

0.03 (0.01)

-0.14(0.19)

-0.11 (-0.24;-0.03)

44

  1. c = total effect of the independent variables (i.e. steps/day and aerobic time) on the outcome variable (i.e SBP, DBP, BC, BG),
  2. a = association between the independent variable (e.g. steps/day) and the potential mediator (e.g. percentage body fat).
  3. b = association between the potential mediator and the outcome variable was assessed, controlled for the independent variable.
  4. c’ = direct effect of the independent variable on the outcome variable was determined.
  5. ab = indirect effects of the independent variable on the outcome variable through the proposed mediator.
  6. % mediation = percentage mediation of the potential mediator (a*b/c).
  7. SE: Standard error.
  8. values represented in bold indicate significant associations.
  9. SBP- systolic blood pressure.
  10. DBP- diastolic blood pressure.
  11. BC- blood cholesterol.
  12. BG- blood glucose.