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Table 3 Lipids, HbA1c and blood pressure: values and target level attainment at inclusion and after 4 months

From: Characteristics, management and attainment of lipid target levels in diabetic and cardiac patients enrolled in Disease Management Program versus those in routine care: LUTZ registry

Parameter

Type-2 Diabetes Mellitus

 

DM in DMP

n = 10110

DM not in DMP

n = 5101

p-value*

Lipids

Inclusion

After 4 months

Inclusion

After 4 months

 

LDL-C; mg/dl (mean ± SD)

129.5 ± 38.9

111.9 ± 30.4

133.5 ± 40.4

113.5 ± 31.1

<0.0001

LDL-C < 100 mg/dl

23.9%

38.3%

21.3%

36.9%

<0.01

LDL-C target level attained**

46.5%

59.6%

35.0%

56.5%

<0.0001

LDL-C target level not attained**

48.9%

30.9%

59.5%

32.4%

<0.001

Total cholesterol, mg/dl (mean ± SD)

218.1 ± 50.5

195.5 ± 38.7

223.8 ± 52.2

198.0 ± 39.5

<0.0001

HDL-C, mg/dl (mean ± SD)

51.2 ± 13.3

52.4 ± 12.8

51.0 ± 13.2

52.3 ± 12.6

0.49

Triglycerides, mg/dl

(mean ± SD)

199.7 ± 96.7

179.5 ± 82.4

201.6 ± 95.9

181.7 ± 84.5

0.11

Blood glucose

     

HbA1c, % (mean ± SD)

7.1 ± 1.1

6.9 ± 1.0

7.1 ± 1.2

6.8 ± 1.0

<0.001

Blood pressure, mmHg

     

Systolic (mean ± SD)

138.1 ± 14.9

134.7 ± 13.4

138.8 ± 15.0

134.8 ± 13.4

<0.05

Diastolic (mean ± SD)

81.3 ± 8.5

79.9 ± 7.8

81.8 ± 8.7

80.3 ± 7.8

<0.001

Parameter

Coronary Heart Disease

 

CHD in DMP

n = 6259

CHD not in DMP

n = 7963

p-value*

Lipids

Inclusion

After 4 months

Inclusion

After 4 months

 

LDL-C; mg/dl (mean ± SD)

122.1 ± 38.0

104.6 ± 27.7

131.6 ± 41.7

109.7 ± 30.9

<0.0001

LDL-C < 100 mg/dl

30.6%

49.8%

23.8%

43.3%

<0.0001

LDL-C target level attained**

42.4%

65.7%

34.5%

60.6%

<0.0001

LDL-C target level not attained**

53.8%

25.7%

61.8%

30.2%

<0.0001

Total cholesterol, mg/dl (mean ± SD)

206.5 ± 48.7

184.8 ± 35.8

219.9 ± 54.0

192.7 ± 39.6

<0.0001

HDL-C, mg/dl (mean ± SD)

51.4 ± 12.8

52.3 ± 12.3

52.4 ± 13.7

53.6 ± 13.1

<0.01

Triglycerides, mg/dl

(mean ± SD)

170.9 ± 85.1

156.7 ± 72.1

178.1 ± 87.8

160.0 ± 74.1

<0.0001

Blood glucose

     

HbA1c, % (mean ± SD)

6.2 ± 0.9

6.2 ± 0.8

6.1 ± 0.9

6.1 ± 0.8

0.09

Blood pressure, mmHg

     

Systolic (mean ± SD)

132.6 ± 14.6

130.3 ± 12.9

135.2 ± 15.1

131.8 ± 12.7

<0.0001

Diastolic (mean ± SD)

79.6 ± 8.3

78.7 ± 7.7

80.9 ± 8.6

79.6 ± 7.6

<0.0001

  1. * p-values refer to difference between DMP and non-DMP patients in the respective indication at inclusion
  2. ** according to physician assessment (not according to guidelines)
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