Table 3 Medical risk factors – surgery
comparison with all control subjects | |||||||||
|---|---|---|---|---|---|---|---|---|---|
Risk factor | n total | mean (SD) or % | crude estimate | age and sex adjusted estimate | age, sex and education adjusted estimate | ||||
cases n = 69 | controls n = 224 | OR (95% CI) | p | OR (95% CI) | p | OR (95% CI) | p | ||
surgery, ever | 292 | 94.1 | 95.1 | 0.83 (0.25–2.68) | 0.751 | 0.94 (0.28–3.13) | 0.921 | 0.99 (0.29–3.37) | 0.984 |
number of operations | 292 | 3.04 (1.71) | 4.33 (2.76) | 0.93 (0.81–1.06) | 0.260 | 0.94 (0.82–1.08) | 0.377 | 0.94 (0.82–1.09) | 0.410 |
neurological surgery | 289 | 10.8 | 7.6 | 1.47 (0.58–3.71) | 0.416 | 1.51 (0.59–3.82) | 0.388 | 1.24 (0.46–3.33) | 0.672 |
neurological surgery (> 1980) | 289 | 4.6 | 1.8 | 2.66 (0.58–12.21) | 0.208 | 2.92 (0.63–13.60) | 0.173 | 2.26 (0.39–13.04) | 0.362 |
ophthalmological surgery | 289 | 15.4 | 20.5 | 0.70 (0.33–1.49) | 0.357 | 0.72 (0.33–1.59) | 0.417 | 0.79 (0.35–1.78) | 0.574 |
ophthalmological surgery (> 1980) | 289 | 15.4 | 8.5 | 1.96 (0.86–4.46) | 0.108 | 2.23 (0.94–5.28) | 0.068 | 2.67 (1.10–6.49) | 0.030 |
abdominal surgery | 288 | 35.9 | 50.5 | 0.55 (0.31–0.98) | 0.042 | 0.56 (0.31–1.01) | 0.054 | 0.53 (0.29–0.98) | 0.041 |
abdominal surgery (> 1980) | 288 | 25.0 | 18.8 | 1.44 (0.75–2.79) | 0.273 | 1.49 (0.77–2.88) | 0.241 | 1.44 (0.72–2.85) | 0.300 |
appendectomy | 292 | 22.1 | 37.5 | 0.47 (0.25–0.89) | 0.020 | 0.49 (0.26–0.94) | 0.032 | 0.55 (0.28–1.05) | 0.071 |
appendectomy (> 1980) | 292 | 4.4 | 22.7 | 0.16 (0.05–0.52) | 0.002 | 0.16 (0.05–0.54) | 0.003 | 0.16 (0.05–0.55) | 0.003 |
gastro- or colonoscopy | 285 | 24.6 | 44.2 | 0.41 (0.22–0.78) | 0.007 | 0.43 (0.22–0.81) | 0.010 | 0.45 (0.23–0.87) | 0.017 |
gastro-/colonoscopy (> 1980) | 285 | 9.8 | 16.5 | 0.55 (0.22–1.37) | 0.201 | 0.58 (0.23–1.46) | 0.250 | 0.59 (0.23–1.49) | 0.260 |
gynaecological surgery1 | 63 | 50.0 | 69.2 | 0.44 (0.16–1.27) | 0.130 | 0.43 (0.15–1.25) | 0.121 | 0.48 (0.16–1.45) | 0.194 |
gynaecological surgery (> 1980)1 | 63 | 25.0 | 33.3 | 0.67 (0.21–2.08) | 0.485 | 0.57 (0.17–1.94) | 0.371 | 0.77 (0.21–2.80) | 0.694 |
orthopaedic surgery | 293 | 52.2 | 20.5 | 4.22 (2.38–7.49) | 0.000 | 4.41 (2.47–7.89) | 0.000 | 4.77 (2.60–8.83) | 0.000 |
orthopaedic surgery (> 1980) | 293 | 44.9 | 20.1 | 3.25 (1.82–5.77) | 0.000 | 3.39 (1.89–6.08) | 0.000 | 3.55 (1.94–6.49) | 0.000 |
tonsillectomy | 292 | 35.3 | 36.6 | 0.94 (0.54–1.66) | 0.844 | 0.93 (0.53–1.65) | 0.806 | 1.04 (0.58–1.88) | 0.889 |
tonsillectomy (> 1980) | 292 | 2.9 | 23.7 | 0.10 (0.02–0.41) | 0.002 | 0.10 (0.02–0.40) | 0.001 | 0.05 (0.01–0.36) | 0.003 |
organ transplantation | 292 | 1.5 | 0.5 | 3.33 (0.21–53.93) | 0.397 | 3.36 (0.20–55.81) | 0.398 | 2.69 (0.16–45.67) | 0.494 |