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Table 2 Use of data gathered to define the organizational model.

From: Can colorectal cancer mass-screening organization be evidence-based? Lessons from failures: The experimental and pilot phases of the Lazio program

Question

Experimental evidence/elements from

Organizational choices

Which Organizational framework?

▪ Literature on organisation topics

▪ RPHA Mission

Disease management as a factor to achieve effectiveness

Which Screening test?

▪ Literature evidence

▪ European Commission Recommendation [4]

▪ FOBT has a compliance of 3.1 compared to FS [25]

FOBT as screening test

Which FOBT type?

▪ Literature evidence

▪ The immunochemical test had a 20% higher compliance than Guaiac.

▪ Higher variability in the results obtained with the Guaiac test than the immunochemical [21].

Immunochemical test as FOBT test

Which FOBT provider?

▪ The compliance to the FOBT with GPs was 3.4 times higher than compliance with the hospital, independent of the type of test and geographical area [20]

General Practitioners as main provider

What the GPs think about screening? What they can do?

▪ GPs currently do not correctly follow up a positive FOBT [18].

▪ There was high variability among GPs: GPs with a heavy work load and those who incorrectly recommended FOBT for CRCS obtained lower compliance [20]

the GPs are not required to participate in the program, but they receive an economic incentive if they do.

Reference diagnostic Centre

▪ Number of CRC cases treated by hospital in the previous 3 yrs plus a guarantee of accessibility in rural areas

▪ A shared system of quality indicators and standards

▪ Attending a re-training course

▪ Centres belonging to Hospitals that have > 500 patients

▪ Centres complying with quality indicators

Why people do not respond to screening invitation?

▪ The first reported reason for non-compliance was "lack of time" (30%).

▪ The major determinant of compliance was the distance from the test provider. [22]

Territorial zoning regardless of administrative borders

Who manage the follow up of positives?

▪ GPs undependable for correct follow-up [18]

▪ Gastroenterologists not skilled in managing mass screening criteria [19]

▪ Neither physicians at endoscopy centers nor GPs tend to follow screening guidelines.

▪ Centralized management

▪ Guidelines-based software

Which software for screening management?

▪ Previous breast cancer screening experience about non-efficiency of in-house softwares, different for each Local Health Unit

▪ Mission: disease-management oriented

▪ Web based software

  1. For each question, the experimental evidence or the elements influencing the final choice are reported