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Table 4 Summary of studies reporting comorbidities with diabetes.

From: Prevalence of comorbidity of chronic diseases in Australia

Comorbidity Study

Study Quality Score/8

Arthritis

(%)

Asthma

(%)

CVD

(%)

Dyslipidemia

(%)

Hypertension

(%)

Malignancy

(%)

Mental problem/

depression#

(%)

Osteoporosis

(%)

Diabetes

         

O'Halloran et al, 2003 [42] ≥ 65 yrs n = 2,976 GP encounters (diabetes prevalence 14.4%)

5

20.1

(OA)a

-

23.6

(IHD)a

22.2

52.7

-

9.0#

13.8

NHS 2004–05 [2] ≥ 65 yrs n = 3,212 self-report all conditions (diabetes prevalence 13.7%)

7

51.0

11.0

26.7

-

-

5.4

7.2

 

Thomas and Nestel, 2007 [43] mean age = 65 yrs, n = 3893 NEFRON study, GP diagnosed type 2 diabetes and comorbidities

4

-

-

40.1b

-

-

-

-

-

Bruce et al, 2005 ≥ 40 yrs [38] (mean age 64 yrs) n = 1,273 clinically diagnosed type 2 diabetes, depression GHSc questionnaire, comorbidities self-report validated with hospital records

5

-

-

41.5d

-

51.1

-

31.5#

 

Clarke et al, 2006 [40] ≥ 35 yrs (mean age 64 yrs), n = 20,538, diabetes diagnosed by diabetes medication, HbA1c or hospital diagnosis (primary or secondary ICD-9 250), co-morbidities identified from hospital administrative data (ICD-9 CM)

6

4.0a

(Musc. Dis)

2.9a

(Resp Dis)

12.3e

-

-

5.6

0.9

 

Goldney et al, 2004 [32] ≥ 15 yrs n = 3,010 self-report of doctor diagnosed diabetes (prevalence 5.2%), depression by PRIME-MDf questionnaire.

5

      

23.6#

 

Kemp et al, 2005 [33] ≥ 25 yrs, n = 11,247 AusDiab survey, self-report doctor diagnosed diabetes, confirmed with hypoglycemic drug use or glucose tolerance test (diabetes prevalence 3.9%), clinical measurement of comorbidities.

5

-

-

-

47.1

53.8

-

-

-

Mitchell et al, 1998 [34] ≥ 49 yrs, n = 3,654 self report of doctor diagnosed diabetes (prevalence 5.9%) and comorbidities

6

-

-

54.7

-

57.6

-

-

-

NHS 2004–05 [2] ≥ 25 yrs n = 17,202 self-report all conditions (diabetes prevalence 5.2%)

7

45.4g

12.3g

20.9

-

-

4.8

9.0

 
  1. -, not reported; #, depression; a (OA, osteoarthritis; IHD, ischemic heart disease; CHD, coronary heart disease; CV, cervebrovascular disease; PVD, peripheral vascular disease; Musc. Dis, Musculoskeletal disease (ICD 710–739); Resp. Dis, Respiratory Disorder (ICD 460–519));b (coronary heart disease, cerebrovascular disease and peripheral vascular disease); c General Health Status (GHS) questionnaire, those reported as having at least 2 depressive symptoms were classed as having depression; d coronary heart disease and cerebrovascular disease; e angina, AMI and stroke; f PRIME-MD; primary care evaluation of mental disorders questionnaire, a validated tool used to diagnoses depression/mental disorders; g ≥ 45 years, data for 25 years and over were reported to have a high standard error and were deemed to be used with caution2.