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Table 1 Summary of screening strategies

From: Tuberculosis screening of travelers to higher-incidence countries: A cost-effectiveness analysis

Strategy Pre-travel tuberculin skin test results Interpretation of pre-travel results Intervention
  Test 1 Test 2   
Pre-trip two step tuberculin test Treat converters ≥ 10 mm N/A Baseline latent tuberculosis infection (LTBI) No intervention. Passive diagnosis of TB disease pursued if symptomatic post-travel.
  <10 mm ≥ 10 mm Booster effect; no baseline LTBI No intervention. Passive diagnosis of TB disease pursued if symptomatic post-travel.
  <10 mm <10 mm No LTBI Post-trip tuberculin test. Converters prescribed isoniazid.
Pre-trip two step tuberculin test Treat reactors and converters ≥ 10 mm N/A Baseline LTBI Prescribe isoniazid.
  <10 mm ≥ 10 mm Booster effect No intervention. Passive diagnosis of TB disease pursued if symptomatic post-travel
  <10 mm <10 mm No LTBI Post-trip tuberculin test. Converters prescribed isoniazid
Post-trip tuberculin test None   None One post-trip tuberculin skin test. All reactors (≥ 10 mm) prescribed isoniazid.
Post-trip chest x-ray None   None Chest x-ray post-trip. Persons with radiographic abnormalities compatible with TB, negative workup for active TB, and TST ≥ 5 mm prescribed isoniazid.
No screening No intervention before or after trip. Passive diagnosis of TB disease pursued if symptomatic post-travel.