Exposure scenario | Exposure | Health endpoint | Approximate lifetime increased mortality |
---|---|---|---|
Living in Central London compared to Inverness. | Mix of air pollutants indicated by average PM2.5 = 6.9 μg m-3 higher. | Mortality | 2.8 % Postulated 2.8% higher air pollution related mortality in central London compared to Inverness (see text). |
N.B. Extrapolates from data in the US. May be confounding factors which, if accounted for, would change the excess risk. Time-lag between exposure and effect is uncertain. | |||
Passive smoking – risk to non-smoker at home if spouse smokes. | Mix of pollutants in secondhand smoke. | Mortality | 1.7 % 1.7% lifetime excess IHD mortality risk from passive smoking: average for men and women [36]. |
N.B. Heart disease risk: does not include strokes or the (significantly lower) risk from lung cancer or other illnesses. May be confounding factors/limitations of meta-analysis data. | |||
Chernobyl emergency workers in the 30-km Zone 1986–87. | Radiation exposure: 100 mSv 250 mSv Illustrative of mean (100 mSv) and high (250 mSv) doses: 4% of workers received doses >250 mSv. | Mortality | 0.4 % 1.0 % Predicted 4% risk of fatal cancer for 1000 mSv dose to working age population. |
N.B. Uncertainty in extrapolation from high dose and dose rate Japanese data to these chronic low doses. If the DDREF was not applied, mortality risk would increase by a factor of 2. Time lag between exposure and effect is generally long (> 10 years) for solid cancers, but is shorter (< 15 years) for leukaemia. Note that 134 ARS victims received much higher doses than 250 mSv. |