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Table 3 Onset of severe knee pain at three years in people aged 50 and over with no knee pain at baseline by body mass index (BMI) category.

From: Disabling knee pain – another consequence of obesity: Results from a prospective cohort study

BMI category at baseline   Severe knee pain at 3 years Unadjusted analysis Adjusted analysisa
  n n (%) Relative Risk (RR) (95% Confidence Interval (CI)) RRb (95% CI) Potential cases avoidedc (% of all incident cases) RR (95% CI) RRb (95% CI) Potential cases avoidedc (% of all incident cases)
Normald 939 50 (5.3) 1.00 - - 1.00 - -
Overweight 785 56 (7.1) 1.34 (0.93, 1.94) 1.00 14 (10.1) 1.53 (1.03, 2.26) 1.00 20 (14.4)
Obese 223 33 (14.8) 2.78 (1.84, 4.21) 2.07 (1.39, 3.11) 17 (12.2) 2.79 (1.75, 4.47) 1.85 (1.17, 2.92) 15 (10.8)
Total 1947e 139 (7.1)    31 (22.3)    35 (25.2)
  1. a adjusted for age, gender, deprivation, anxiety, depression, previous knee injury, widespread pain measured at baseline
  2. b obesity category compared to overweight
  3. c number of cases which could have been avoided by reducing overweight people to normal and obese people to overweight
  4. d Normal weight category includes individuals who were underweight
  5. e Total number is smaller than in Table 2, because 49 people had incomplete WOMAC data and severity scores could not be calculated.