Table 2 Comparison of seroprevalence of hepatitis B virus (HBV) markers by different age and vaccine type received in infancy
Age group | Vaccine type | Plasma-derived | Recombinant | Total | P-value |
|---|---|---|---|---|---|
Items | |||||
15 y/o | N [birth cohort] | 410 [1989–91] | 886 [1993–97] | 1296 | |
anti-HBs (+), n | 177 | 307 | 484 | 0.004* | |
(%, 95% CI) | (43.2, 38.4-48.0) | (34.7, 31.6-37.8) | (37.3, 34.3-39.9) | ||
anti-HBs (−), n | 233 | 579 | 812 | ||
(%, 95% CI) | (56.8, 52.0-61.6) | (65.3, 62.2-68.4) | (62.7, 60.1-65.3) | ||
HBsAg (+), n | 7 | 6 | 13 | 0.129 | |
(%, 95% CI) | (1.7, 0.4-3.0) | (0.7, 0.2-1.2) | (1.0, 0.5-1.5) | ||
HBsAg (−), n | 403 | 880 | 1283 | ||
(%, 95% CI) | (98.3, 97.0-99.6) | (99.3, 98.8-99.8) | (99.0, 98.5-99.5) | ||
18 y/o | N [birth cohort] | 2575 [1987–91] | 1295 [1993–94] | 3870 | |
anti-HBs (+), n | 1184 | 529 | 1713 | 0.003* | |
(%, 95% CI) | (46.0, 44.1-47.9) | (40.8, 38.1-43.5) | (44.3, 42.7-45.9) | ||
anti-HBs (−), n | 1391 | 766 | 2157 | ||
(%, 95% CI) | (54.0, 52.1-55.9) | (59.2, 56.5-61.9) | (55.7, 54.1-57.3) | ||
HBsAg (+), n | 40 | 10 | 50 | 0.049* | |
(%, 95% CI) | (1.6, 1.1-2.1) | (0.8, 0.3-1.3) | (1.3, 0.9-1.7) | ||
HBsAg (−), n | 2535 | 1285 | 3820 | ||
(%, 95% CI) | (98.4, 97.9-98.9) | (99.2, 98.7-99.7) | (98.7, 98.3-99.1) |