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Table 3 Multivariate multilevel mixed model for the incidence of TB among HCWs working in three public hospitals in KwaZulu-Natal, South Africa (January 2006 – December 2010) (n = 1,313)

From: Tuberculosis among health care workers in KwaZulu-Natal, South Africa: a retrospective cohort analysis

Variable*

Unadjusted IRR (95% CI)

Adjusted IRR (95% CI)

Ward where HCW worked**

 

TB ward

2.87 (1.67 – 4.93)

2.03 (1.11 – 3.71)

General ward

1.73 (1.15 – 2.60)

1.50 (0.93 – 2.44)

Pediatric ward

2.70 (1.68 – 4.34)

1.82 (1.07 – 3.10)

Outpatient department

1.99 (1.17– 3.40)

2.08 (1.23 – 3.52)

Primary health care center

2.15 (1.18 – 3.89)

1.49 (0.76 – 2.91)

Stores/workshop

1.95 (0.92 – 4.13)

2.38 (1.06 – 5.34)

MDR-TB ward

0.25 (0.06 – 1.08)

0.34 (0.08 – 1.51)

Wards worked in

  

1 ward

Ref

Ref

> 1 ward

2.03 (1.37 – 3.02)

1.40 (0.84 – 2.34)

Age in years

0.99 (0.97 – 1.01)

0.97 (0.94 – 1.00)

Years worked in hospital

1.01 (0.98 – 1.03)

1.02 (0.99 – 1.06)

HIV status

 

HIV-negative

Ref

Ref

HIV-positive

5.35 (2.58 – 11.10)

3.20 (1.54 – 6.66)

HIV status not recorded

1.16 (0.67 – 2.01)

0.89 (0.52 – 1.55)

Occupation

 

Administrative

Ref

Ref

Paramedical staff

2.39 (0.93 – 6.14)

2.25 (0.80 – 6.29)

Support staff

1.81 (0.81 – 4.02)

2.24 (0.95– 5.29)

Clinical staff

1.64 (0.76 – 3.51)

1.43 (0.61 – 3.32)

  1. *Variables included as fixed effects were: history of work in a TB ward, general ward, pediatric ward, outpatient department, primary health care center, stores/workshop, number of wards HCWs had worked in (1 ward vs. >1 ward), age (centered at the mean age of 40 years), duration of employment (continuous variable calculated as the duration of employment in the facility minus the total person-time in years, HIV status, and occupation.
  2. **Referent group for each ward is no history of working in that ward.
  3. Bold indicates significant findings at p-value <0.05.