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Table 3 Multivariate multilevel mixed model for the incidence of TB among HCWs working in three public hospitals in KwaZulu-Natal, South Africa (January 2006 – December 2010) (n = 1,313)

From: Tuberculosis among health care workers in KwaZulu-Natal, South Africa: a retrospective cohort analysis

Variable* Unadjusted IRR (95% CI) Adjusted IRR (95% CI)
Ward where HCW worked**  
TB ward 2.87 (1.67 – 4.93) 2.03 (1.11 – 3.71)
General ward 1.73 (1.15 – 2.60) 1.50 (0.93 – 2.44)
Pediatric ward 2.70 (1.68 – 4.34) 1.82 (1.07 – 3.10)
Outpatient department 1.99 (1.17– 3.40) 2.08 (1.23 – 3.52)
Primary health care center 2.15 (1.18 – 3.89) 1.49 (0.76 – 2.91)
Stores/workshop 1.95 (0.92 – 4.13) 2.38 (1.06 – 5.34)
MDR-TB ward 0.25 (0.06 – 1.08) 0.34 (0.08 – 1.51)
Wards worked in   
1 ward Ref Ref
> 1 ward 2.03 (1.37 – 3.02) 1.40 (0.84 – 2.34)
Age in years 0.99 (0.97 – 1.01) 0.97 (0.94 – 1.00)
Years worked in hospital 1.01 (0.98 – 1.03) 1.02 (0.99 – 1.06)
HIV status  
HIV-negative Ref Ref
HIV-positive 5.35 (2.58 – 11.10) 3.20 (1.54 – 6.66)
HIV status not recorded 1.16 (0.67 – 2.01) 0.89 (0.52 – 1.55)
Occupation  
Administrative Ref Ref
Paramedical staff 2.39 (0.93 – 6.14) 2.25 (0.80 – 6.29)
Support staff 1.81 (0.81 – 4.02) 2.24 (0.95– 5.29)
Clinical staff 1.64 (0.76 – 3.51) 1.43 (0.61 – 3.32)
  1. *Variables included as fixed effects were: history of work in a TB ward, general ward, pediatric ward, outpatient department, primary health care center, stores/workshop, number of wards HCWs had worked in (1 ward vs. >1 ward), age (centered at the mean age of 40 years), duration of employment (continuous variable calculated as the duration of employment in the facility minus the total person-time in years, HIV status, and occupation.
  2. **Referent group for each ward is no history of working in that ward.
  3. Bold indicates significant findings at p-value <0.05.