Table 2 Subgroup analysis of risk ratios per 100 ug/day increase in dietary folate intake and per 5 nmol/L increase in serum folate levels for prostate cancer
From: Folate intake, serum folate levels, and prostate cancer risk: a meta-analysis of prospective studies
Cancer sites | Group | RR and 95% CI | P value | Heterogeneity (%) | P value for heterogeneity |
|---|---|---|---|---|---|
Dietary folate intake | Country | ||||
Europe | 1.00 (0.98-1.02) | 0.920 | 0.0 | 0.692 | |
Other | 1.01 (0.99-1.03) | 0.232 | 0.0 | 0.677 | |
Effect estimate | |||||
RR | 1.00 (0.98-1.02) | 0.743 | 0.0 | 0.361 | |
HR | 1.01 (0.99-1.03) | 0.421 | 0.0 | 0.682 | |
Follow-up (year) | |||||
15 or greater | 1.01 (0.99-1.03) | 0.421 | 0.0 | 0.682 | |
<15 | 1.00 (0.98-1.02) | 0.743 | 0.0 | 0.361 | |
Adjusted age | |||||
Yes | 1.01 (0.99-1.02) | 0.601 | 0.0 | 0.577 | |
No | 1.01 (0.98-1.03) | 0.548 | 0.0 | 0.432 | |
Adjusted BMI | |||||
Yes | 1.01 (0.98-1.03) | 0.548 | 0.0 | 0.432 | |
No | 1.01 (0.99-1.02) | 0.601 | 0.0 | 0.577 | |
Adjusted alcohol consumption | |||||
Yes | 1.01 (0.98-1.03) | 0.548 | 0.0 | 0.432 | |
No | 1.01 (0.99-1.02) | 0.601 | 0.0 | 0.577 | |
Serum folate levels | Country | ||||
Europe | 1.05 (1.00-1.11) | 0.062 | 23.2 | 0.272 | |
Other | 1.03 (0.82-1.29) | 0.798 | - | - | |
Effect estimate | |||||
RR | 1.09 (0.99-1.20) | 0.079 | - | - | |
OR | 1.03 (0.99-1.07) | 0.132 | 0.0 | 0.440 | |
Follow-up (year) | |||||
15 or greater | 1.02 (0.98-1.06) | 0.323 | - | - | |
<15 | 1.09 (1.02-1.18) | 0.015 | 0.0 | 0.769 | |
Adjusted age | |||||
Yes | 1.03 (0.82-1.29) | 0.798 | - | - | |
No | 1.05 (1.00-1.11) | 0.062 | 23.2 | 0.272 | |
Adjusted BMI | |||||
Yes | 1.06 (0.99-1.14) | 0.102 | 48.0 | 0.146 | |
No | 1.05 (0.91-1.21) | 0.507 | 0.0 | 0.845 | |
Adjusted smoking | |||||
Yes | 1.06 (0.99-1.14) | 0.102 | 48.0 | 0.146 | |
No | 1.05 (0.91-1.21) | 0.507 | 0.0 | 0.845 | |