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Table 4 Univariate and multivariate analysis for the associated and predicting demographic and health status characteristics, to PN

From: Prevalence of peripheral neuropathy and its associated demographic and health status characteristics, among people on antiretroviral therapy in Rwanda

Characteristics   Prevalence (%) of PN (n = 300) Univariate models Multivariate models
Odds ratio (OR) (95% CI) p-value Adjusted odds ratio (aOR) (95% CI) p-value
Age   42 (±9.2) 1.1 (1.0, 1.1) <0.001 1.1 (1.0, 1.1) <0.001*
Gender Female 210 (57) 1.0 (ref) 0.25   
  Male 87 (63) 1.3 (0.8, 1.9)    
Education None 73 (65) 1.0 (ref)   1.0 (ref)  
  Primary 128 (51) 0.6 (0.4, 0.9) 0.01 0.6 (0.3, 1.0) 0.04*
  > = Secondary 99 (69) 1.2 (0.7, 2.0) 0.55 0.6 (0.3, 1.3) 0.2
Occupation Public employed 29 (69) 1.0 (ref)   1.0 (ref)  
  Peasant/Farmer 106 (47) 0.4 (0.2, 0.8) 0.01 0.9 (0.3, 2.2) 0.76
  Self employed 56 (63) 0.8 (0.3, 1.7) 0.5 0.3 (0.1, 0.9) 0.03
  Unemployed 109 (72) 1.1 (0.5, 2.4) 0.74 0.6 (0.2, 1.4) 0.22
Marital status Single 18 (51) 1.0 (ref)    
  Married 112 (48) 0.9 (0.4, 1.8) 0.75   
  Divorced/Separated 63 (78) 3.3 (1., 4) <0.01   
  Window/Widower 107 (66) 1. 9 (0.9, 4.) 0.09   
Setting/Residence Urban 200 (78) 1.0 (ref)   1.0 (ref)  
  Rural 99 (40) 0.2 (0.1, 0.3) <0.001 0.1 (0.06, 0.3) <0.001*
CD4 cell count <=350 91 (49) 1.0 (ref)    
  >350 209 (59) 1.0 (0.7, 1.5) 1.008   
Duration since HIV diagnosis 0 – 3 years ago 84 (54) 1.0 (ref)   1.0 (ref)  
  4 – 6 years ago 96 (51) 0.9 (0.6, 1.4) 0.60 0.6 (0.3,1.1) 0.08
  7 and above yrs 120 (73) 2.3 (1.5, 3.7) <0.001 1.4 (0.7, 3.0) 0.33
Current ARV regimen Non D4T containing 247 (61) 1.0 (ref)    
  D4T containing 53 (51) 1.0 (0.4, 1.0) 0.06   
Duration on ARVs (in years) 0 – 1 52 (42) 1.0 (ref)   1.0 (ref)  
  1 – 3 101 (64) 2.4 (1.5, 3.8) <0.001 2.6 (1.4, 4.8) 0.001
  4 – 6 108 (64) 2.4 (1.5, 3.9) <0.001 2.0 (10, 4.1) 0.05
  7 and above 39 (70) 3.1 (1.6, 6.1) 0.001 2.2 (0.8, 5.9) 0.1
ARV regimen changes None 48 (57) 1.0 (ref)    
  Once 150 (56) 0.9 (0.6, 1.5) 0.80   
  Two and more 92 (68) 1.6 (1.0, 2.8) 0.08   
ARV started with Non D4T containing 104 (63) 1.0 (ref)    
  D4T containing 196 (57) 0.8 (0.6, 1.2) 0.27   
  1. *Denotes significant p-value for the association of the characteristics with PN in a multivariate model, CI = Confidence Interval.