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Table 4 Univariate and multivariate analysis for the associated and predicting demographic and health status characteristics, to PN

From: Prevalence of peripheral neuropathy and its associated demographic and health status characteristics, among people on antiretroviral therapy in Rwanda

Characteristics

 

Prevalence (%) of PN (n = 300)

Univariate models

Multivariate models

Odds ratio (OR) (95% CI)

p-value

Adjusted odds ratio (aOR) (95% CI)

p-value

Age

 

42 (±9.2)

1.1 (1.0, 1.1)

<0.001

1.1 (1.0, 1.1)

<0.001*

Gender

Female

210 (57)

1.0 (ref)

0.25

  
 

Male

87 (63)

1.3 (0.8, 1.9)

   

Education

None

73 (65)

1.0 (ref)

 

1.0 (ref)

 
 

Primary

128 (51)

0.6 (0.4, 0.9)

0.01

0.6 (0.3, 1.0)

0.04*

 

> = Secondary

99 (69)

1.2 (0.7, 2.0)

0.55

0.6 (0.3, 1.3)

0.2

Occupation

Public employed

29 (69)

1.0 (ref)

 

1.0 (ref)

 
 

Peasant/Farmer

106 (47)

0.4 (0.2, 0.8)

0.01

0.9 (0.3, 2.2)

0.76

 

Self employed

56 (63)

0.8 (0.3, 1.7)

0.5

0.3 (0.1, 0.9)

0.03

 

Unemployed

109 (72)

1.1 (0.5, 2.4)

0.74

0.6 (0.2, 1.4)

0.22

Marital status

Single

18 (51)

1.0 (ref)

   
 

Married

112 (48)

0.9 (0.4, 1.8)

0.75

  
 

Divorced/Separated

63 (78)

3.3 (1., 4)

<0.01

  
 

Window/Widower

107 (66)

1. 9 (0.9, 4.)

0.09

  

Setting/Residence

Urban

200 (78)

1.0 (ref)

 

1.0 (ref)

 
 

Rural

99 (40)

0.2 (0.1, 0.3)

<0.001

0.1 (0.06, 0.3)

<0.001*

CD4 cell count

<=350

91 (49)

1.0 (ref)

   
 

>350

209 (59)

1.0 (0.7, 1.5)

1.008

  

Duration since HIV diagnosis

0 – 3 years ago

84 (54)

1.0 (ref)

 

1.0 (ref)

 
 

4 – 6 years ago

96 (51)

0.9 (0.6, 1.4)

0.60

0.6 (0.3,1.1)

0.08

 

7 and above yrs

120 (73)

2.3 (1.5, 3.7)

<0.001

1.4 (0.7, 3.0)

0.33

Current ARV regimen

Non D4T containing

247 (61)

1.0 (ref)

   
 

D4T containing

53 (51)

1.0 (0.4, 1.0)

0.06

  

Duration on ARVs (in years)

0 – 1

52 (42)

1.0 (ref)

 

1.0 (ref)

 
 

1 – 3

101 (64)

2.4 (1.5, 3.8)

<0.001

2.6 (1.4, 4.8)

0.001

 

4 – 6

108 (64)

2.4 (1.5, 3.9)

<0.001

2.0 (10, 4.1)

0.05

 

7 and above

39 (70)

3.1 (1.6, 6.1)

0.001

2.2 (0.8, 5.9)

0.1

ARV regimen changes

None

48 (57)

1.0 (ref)

   
 

Once

150 (56)

0.9 (0.6, 1.5)

0.80

  
 

Two and more

92 (68)

1.6 (1.0, 2.8)

0.08

  

ARV started with

Non D4T containing

104 (63)

1.0 (ref)

   
 

D4T containing

196 (57)

0.8 (0.6, 1.2)

0.27

  
  1. *Denotes significant p-value for the association of the characteristics with PN in a multivariate model, CI = Confidence Interval.
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