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Table 3 Cox regression models of the association between quintiles of mental component summary score (MCS) of the SF-12 and adverse outcomes

From: Association between physical and mental health-related quality of life and adverse outcomes; a retrospective cohort study of 5,272 Scottish adults

  Model 1 Model 2 Model 3
  HR (95% CI) P value HR (95% CI) P value HR (95% CI) P value
All-cause death      
MCS quintile      
  1 (worst) 1.61 (1.24, 2.10) <0.001 1.33 (1.01, 1.75) 0.041 1.25 (0.95, 1.65) 0.117
  2 1.04 (0.76, 1.41) 0.824 1.00 (0.73, 1.37) 0.991 1.00 (0.73, 1.37) 0.998
  3 0.83 (0.59, 1.15) 0.259 0.92 (0.66, 1.28) 0.603 0.88 (0.63, 1.23) 0.463
  4 0.66 (0.47, 0.91) 0.012 0.77 (0.56, 1.08) 0.128 0.76 (0.55, 1.06) 0.104
  5 (best) 1.00 - 1.00 - 1.00 -
Cancer registration      
MCS quintile      
  1 (worst) 0.81 (0.59, 1.10) 0.171 0.75 (0.55, 1.03) 0.077 0.75 (0.55, 1.03) 0.079
  2 0.75 (0.55, 1.03) 0.077 0.75 (0.54, 1.03) 0.075 0.74 (0.54, 1.03) 0.071
  3 0.70 (0.51, 0.97) 0.033 0.73 (0.52, 1.01) 0.055 0.72 (0.52, 1.01) 0.054
  4 0.78 (0.58, 1.06) 0.111 0.83 (0.61, 1.12) 0.215 0.82 (0.61, 1.11) 0.206
  5 (best) 1.00 - 1.00 - 1.00 -
Coronary heart disease hospitalisation/death    
MCS quintile      
  1 (worst) 0.91 (0.56, 1.48) 0.715 0.84 (0.51, 1.37) 0.480 0.84 (0.51, 1.38) 0.499
  2 0.60 (0.35, 1.05) 0.072 0.61 (0.35, 1.06) 0.077 0.61 (0.35, 1.06) 0.082
  3 0.55 (0.31, 0.97) 0.039 0.59 (0.33, 1.05) 0.071 0.59 (0.33, 1.05) 0.073
  4 0.75 (0.46, 1.22) 0.252 0.79 (0.48, 1.29) 0.352 0.80 (0.49, 1.30) 0.363
  5 (best) 1.00 - 1.00 - 1.00 -
  1. Higher quintile indicate better mental health status; MCS, mental component summary quintile (score): 1 (<47), 2 (47 to 52.9), 3 (53 to 55.9), 4 (56 to 58), 5 (>58); HR, hazard ratio; CI, Confidence interval; Model 1 adjusted for age; Model 2 adjusted for age, sex, SIMD, education level, smoking status, alcohol consumption, hypertension and diabetes; Model 3 adjusted for same covariates as Model 2 plus body mass index.