Assumption | Implication for modelling |
---|---|
6-month behaviours from the trial are assumed to represent year 1 behaviours in the model. | May over-estimate the duration of U@Uni behavioural treatment effects by 6 months. |
Health Survey for England complete case data represents behavioural patterns in the general population that is represented in the ONS Life Tables. | Complete cases from Health Survey for England may be atypical and not representative of the general population in some way (unclear effect on results) |
Probability of death aged >100 years = 1 | May under-estimate life expectancy increases as a result of U@Uni. |
Assumes health behaviours from Health Survey for England when aged over 90 are equal to those when aged 90 | Health behaviours of people aged over 90 may be different from those of people aged 90 in some way (unclear effect on results). |
Assumes relationship between alcohol and mortality risk is linear and between physical activity or fruit and vegetables and mortality risk is logarithmic (to avoid negative values for hazard ratios) | The shape of the true relationship between the health behaviours and mortality risk may have a different functional form (unclear effect on results). |
Hazard ratio for 0 portions fruit and vegetables = 1.6 | May under- or over-estimate the increased mortality risk associated with eating no fruit and vegetables (unclear effect on results). |
Hazard ratio for 0 minutes of physical activity = 1.6 | May under- or over-estimate the increased mortality risk associated with doing no physical activity (unclear effect on results). |
Except for due to the effect of U@Uni an individuals’ fruit and vegetable consumption, physical activity, and alcohol consumption measured 6-months after university are assumed to stay on the same age-specific percentile rank from the general population throughout their lifetime | Individuals’ health behaviours could be expected to vary more than this over a lifetime (unclear effect on results). |
Except for due to the effect of U@Uni an individuals’ smoking status measured 6-months after university is assumed to stay fixed throughout their lifetime | Individuals’ smoking status could be expected to vary more than this over a lifetime (unclear effect on results). |
Health behaviour change decays linearly up to the year of the maximum length of the treatment effect | Behaviour change may decay non-linearly (unclear effect on results). |
Hazard ratios for the effect of health behaviours on mortality risk are age independent | The relative effect of health behaviours on mortality risk may vary with age (unclear effect on results). |