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Table 1 Effect of community based interventions on the coverage of commodities/services for diarrhea and pneumonia

From: Effect of community based interventions on childhood diarrhea and pneumonia: uptake of treatment modalities and impact on mortality

 

Quality Assessment

Summary of Findings

 

Directness

No of events

 

No of studies

Design

Limitations

Consistency

Generalizability to population of interest

Generalizability to intervention of interest

Intervention

Control

Relative Risk (95% CI)

Care seeking rates for Pneumonia: moderate outcome specific quality of evidence

Two

RCT/Quasi

No significant heterogeneity so a fixed effect model used

Both studies suggest benefit

One study from Asia and one from Africa

WHO case management by local health workers

344

327

1.13 [1.08, 1.18]

Care seeking rates for Diarrhea: moderate outcome specific quality of evidence

Four

CRCT

Significant heterogeneity so a random effect model used

Two studies show benefit

All studies from South Asia

Promotion of use of ORS and zinc by CHWs

3562

4691

1.09 [1.06, 1.12]

ORS use for the management of diarrhea: moderate/low outcome specific quality of evidence

Six

RCT/Quasi

Significant heterogeneity so a random effect model used

All the studies suggest benefit

All studies are from Asia

All the studies had community education while four studies had combined intervention of promotion and zinc therapy and two had free distribution of ORS

10446

3990

2.60 [1.59, 4.27]

Two

Before/After

No major limitation

All the studies suggest benefit

Both studies were from Africa

One study had combined intervention of promotion of zinc therapy

143

86

1.75 [1.48, 2.07]

Use of zinc for the management of diarrhea: moderate outcome specific quality of evidence

Four

cRCT

Significant heterogeneity across studies so a random effect model used

All Studies suggest benefit

All studies from South Asia

CHWs provided education and promoted use of ORS and zinc

5554

14

29.79 [12.33, 71.97]

Antibiotic Use for Diarrhea: moderate outcome specific quality of evidence

Four

cRCT

Significant heterogeneity across studies so a random effect model used

All studies suggested a decline in the use of antibiotics

All studies from South Asia

CHWs provided education and promoted use of ORS and zinc

639

3083

0.25 [0.12, 0.51]

One

Before/After

 

Decline in the use of antibiotics

Study conducted in Mali

CHWs provided education and promoted use of ORS and zinc

104

130

0.83 [0.69, 0.99]

Antibiotic Use for Pneumonia: moderate outcome specific quality of evidence

One

Quasi

  

Study Conducted in Uganda

WHO case management by local health workers

187

319

1.13 [0.99, 1.30]

Treatment Failure Rates for ARI/Pneumonia: moderate outcome specific quality of evidence

Two

cRCT

No significant heterogeneity so a fixed effect model used

Both studies suggest benefit

One study from Asia and one from Africa

WHO case management by local health workers

228

314

0.60 [0.51, 0.70]