45, 76, 108
|
1700 h (check in)
|
Blood, urine
|
Measure BP, PR, RR and temperature; abbreviated physical examination and medical history; illicit drug, alcohol and cotinine testing; pregnancy testing; collection of diary and cigarette butts; clinical laboratory tests; electrocardiography; lung- function tests; dinner
|
1900 h
|
None
|
Start 24 h urine collection, monitoring of cigarette consumption and collection of filters
|
2100 h
|
None
|
Snack
|
46, 77, 109
|
0700 h
|
Blood
|
Measure BP, PR, RR and temperature; measure creatinine in serum; biomarkers and gene expression
|
0800 h
|
None
|
Breakfast
|
1000 h
|
None
|
Administer sensory questionnaire; administer quality-of-life and diet and lifestyle questionnairesa
|
1200 h
|
None
|
Lunch
|
1500 h
|
None
|
Measure exhaled CO
|
1700 h
|
Saliva
|
Cotinine testing; dinner
|
1900 h
|
None
|
End 24 h urine collection, monitoring of cigarette consumption and collection of filters; dispense interventional products and cigarette butt collection tins for use at home, remind participants of instructions for diet and completion of diaries
|